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Leiomyomatosis peritonealis disseminata (LPD) is an exceedingly rare, usually benign condition that clinically simulates a disseminated malignancy. It occurs predominantly in women of childbearing age. Approximately 50 cases of LPD have been described in the literature with 2 cases reported to have progressed into aggressive leiomyosarcomas. Excessive hormonal stimulation appears to correlate with LPD development since it is commonly associated with pregnancy. Conservative treatment with long-term follow-up is recommended because of LPD's generally indolent clinical course. We report 5 cases of LPD with a review of the literature.

We describe two rare cervical tumors having morphologic features closely resembling those of the nasopharyngeal lymphoepithelioma. This entity has historically been classified as a subtype of squamous cell carcinoma, but after reviewing the literature and the two cases presented here, we propose that this tumor is a distinct carcinoma of the cervix that differs from squamous cell carcinoma in that it carries a more favorable prognosis, typically affects a younger population of women, is more prevalent in noncaucasian populations (especially those of Asian descent), and lacks a clearly defined association with infection due to human papilloma virus (HPV).

Epithelial ovarian cancer (EOC) continues to be an academically challenging and clinically problematic disease. Even with recent advances, the overall 5-year survival is still 31% to 42% in various studies. Deaths from EOC outnumber those due to cervical, vulvar, and endometrial carcinomas combined. Screening for EOC has shown limited success in early detection. The Pap smear is not a dependable tool in EOC screening, though at times it can be the first evidence of ovarian disease. We report a case of EOC that was diagnosed during evaluation of an abnormal Pap smear. On completion of evaluation, stage IIIA endometrioid-type adenocarcinoma of the ovary was diagnosed. Occult EOC should be considered in patients with abnormal findings on cervical cytology after cervical and uterine carcinomas are ruled out.

Leiomyomatosis peritonealis disseminata (LPD) is an exceedingly rare, usually benign condition that clinically simulates a disseminated malignancy. It occurs predominantly in women of childbearing age. Approximately 50 cases of LPD have been described in the literature with 2 cases reported to have progressed into aggressive leiomyosarcomas. Excessive hormonal stimulation appears to correlate with LPD development since it is commonly associated with pregnancy. Conservative treatment with long-term follow-up is recommended because of LPD's generally indolent clinical course. We report 5 cases of LPD with a review of the literature.

We have presented a case of paratesticular myxoma and have described the clinical history, findings on light microscopy and immunohistochemistry, and possible pathogenesis. Although primary paratesticular myxoma is a rare lesion, it should be considered in the differential diagnosis of intrascrotal mesenchymal tumors.

We report a case of basal cell carcinoma arising in a previously radiated field after treatment of cervical cancer. Our search of the literature yielded no other case of basal cell carcinoma due to irradiation for cervical carcinoma.

Cantharidin, or Spanish fly, is a lipid soluble irritant extracted from the blister beetle. Manifestations of cantharidin poisoning range from local vesiculobullous formation to gross hematuria, myocardial damage, denudation of the gastrointestinal tract, and occasionally death. Despite the wide spectrum of clinical symptomatology, the available information on this subject is extremely scanty. We have attempted the first review of this subject in this century. Currently cantharidin is the active ingredient in various wart removal compounds. The blister beetle has a ubiquitous distribution, with many species found in the southeastern United States. Although most case reports concern adults, the potential for pediatric poisoning is great. Treatment is primarily supportive.

Review of 3,084 autopsies from 1967 to 1977 at Grady Memorial Hospital Yielded 14 cases of myocardial abscess unassociated with infective endocarditis acceptable for our study. No case was diagnosed ante mortem. Gram-negative organisms, fungi, and Staphylococcus aureus were isolated. Underlying conditions included alcoholic hepatitis, acute myocardial infarction, systemic lupus erythematosus, and various malignancies. The physical examination, chest roentgenogram, and electrocardiogram were not helpful in establishing a diagnosis. complications included pericarditis and congestive heart failure. A high index of suspicion in a debilitated patient not responding to conventional antimicrobial therapy appears to be the only clue to the antemortem diagnosis. Cardiac scintigraphy is promising as a possible means of earlier detection.

A neurilemoma arising in breast tissue is reported. Neurilemomas are usually well circumscribed and non-invasive, but may be confused with cystosarcoma phylloides, particularly in frozen section. Pertinent pathologic findings are described, and the literature is reviewed. Only one case of neurilemoma in the breast has previously been reported.