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Your search keyword '"De Bruin E"' showing total 12 results
Start Over Author "De Bruin E" Journal south african medical journal suid afrikaanse tydskrif vir geneeskunde
12 results on '"De Bruin E"'

1. Metabolism of 14C-labelled L-tryptophan, L-kynurenine and hydroxy-L-kynurenine in miners with scleroderma.

Author

Hankes LV, De Bruin E, Jansen CR, Vorster L, and Schmaeler M

Subjects
Carbon Dioxide metabolism, Humans, Male, Middle Aged, Nicotinic Acids urine, Occupational Diseases urine, Quinolinic Acids urine, Scleroderma, Systemic urine, Kynurenine metabolism, Mining, Occupational Diseases metabolism, Scleroderma, Systemic metabolism, Tryptophan metabolism
Abstract

Six South African White miners were studied with the 2-g L-tryptophan load test and tracer doses of L-tryptophan-7a-14C, L-kynurenine-keto-14C and hydroxy-L-kynurenine-keto-14C. The breath 14CO2 and 14 urinary metabolities were measured. When they were compared with a previous study of American women with scleroderma, similar 14CO2 and tryptophan metabolite excretion patterns were observed in the data from the miners. The labelled quinolinic acid excretion was more significantly elevated in the South African miners' urine than in the urine of the American women. The data from both studies suggest that some patients with scleroderma have an altered step in the tryptophan metabolic pathway after hydroxy-anthranilic acid. What relationship exists between the induction of pulmonary silicosis and the subsequent development of scleroderma, requires additional human studies.

Published
1977

2. Comparative determination of total serum thyroxine. Radio-immunoassay and protein-binding assay.

Author

Bieler EU, Nagel D, and De Bruin EJ

Subjects
Costs and Cost Analysis, Estrogens pharmacology, Humans, Hyperthyroidism blood, Hypothyroidism blood, Iodine Radioisotopes, Radioimmunoassay, Radioligand Assay, Thyroxine blood
Abstract

The precision, accuracy, sensitivity and clinical results of a radio-immunological method for the determination of total serum thyroxine are compared with similar criteria of a competitive protein-binding assay. Application of both methods in the assay of thyroxine in 150 serum samples gave good agreement between the two techniques. The radio-immunoassay offers certain methodological advantages and is considerably less costly than thyroxine determinations in which commercially available kits are used.

Published
1975

4. Suppression of growth hormone release by glucose administration in diabetic individuals.

Author

Bieler EU, Van Rooyen RJ, De Bruin EJ, and Hoog JM

Subjects
Adolescent, Adult, Aged, Blood Glucose, Child, Depression, Chemical, Diabetes Mellitus blood, Diabetes Mellitus drug therapy, Diabetes Mellitus, Type 1 blood, Growth Hormone blood, Humans, Insulin therapeutic use, Male, Middle Aged, Radioimmunoassay, Secretory Rate drug effects, Diabetes Mellitus metabolism, Glucose pharmacology, Growth Hormone metabolism
Published
1973

5. Iron in human bile.

Author

Mekel RC, van der Merwe CJ, de Bruin EJ, and Jansen CR

Subjects
Adult, Female, Humans, Injections, Intravenous, Iron Isotopes, Middle Aged, Time Factors, Bile metabolism, Iron metabolism
Published
1970

7. Some biochemical effects of a mainly fruit diet in man.

Author

Meyer BJ, de Bruin EJ, Du Plessis DG, van der Merwe M, and Meyer AC

Subjects
Black People, Blood Proteins analysis, Cholesterol blood, Electrolytes blood, Follow-Up Studies, Glucose Tolerance Test, Humans, Insulin blood, Kidney Function Tests, Lipids blood, Lipoproteins blood, Liver Function Tests, Nuts, Phospholipids blood, Serum Albumin analysis, Serum Globulins analysis, South Africa, Thyroid Function Tests, Time Factors, Triglycerides blood, Diet, Fruit
Published
1971

8. Diagnostic accuracy of three tests for evaluating the thyroid status. Results of the in vitro assessment of thyroid function and of the 24-hour 131 I-uptake of the thyroid gland.

Author

Bieler EU, van Rooyen RJ, de Bruin EJ, de Villiers LS, and Meyer BJ

Subjects
Chromatography, Ion Exchange, Humans, Hyperthyroidism diagnosis, Hypothyroidism diagnosis, Iodine Radioisotopes, Radioligand Assay, Iodine metabolism, Thyroid Diseases diagnosis, Thyroid Function Tests, Thyroid Gland metabolism, Thyroxine blood
Published
1973

9. Insulin secretion in Bantu with siderosis or hepatoma.

Author

De Bruin EJ and Meyer BJ

Subjects
Adult, Aged, Carcinoma, Hepatocellular blood, Glucose Tolerance Test, Humans, Male, Middle Aged, Time Factors, Carcinoma, Hepatocellular metabolism, Hemosiderosis metabolism, Insulin metabolism, Liver Neoplasms metabolism
Published
1971

10. The half-life of 131 I-insulin in different groups of patients compared with normal subjects.

Author

van Rooyen RJ, de Bruin EJ, Bieler EU, and Hoog JM

Subjects
Blood Protein Electrophoresis, Carrier Proteins, Diabetes Mellitus drug therapy, Half-Life, Humans, Hypoglycemic Agents therapeutic use, Insulin blood, Insulin therapeutic use, Insulin, Long-Acting therapeutic use, Iodine Isotopes, Kidney metabolism, Liver metabolism, Radioimmunoassay, Whole-Body Counting, Diabetes Mellitus metabolism, Insulin metabolism, Kidney Diseases metabolism, Liver Diseases metabolism
Published
1972

12. Some physiological effects of a mainly fruit diet in man.

Author

Meyer BJ, van der Merwe M, Du Plessis DG, de Bruin EJ, and Meyer AC

Subjects
Adult, Ascorbic Acid analysis, Body Weight, Calcium analysis, Calorimetry, Carbohydrates analysis, Clinical Trials as Topic, Female, Follow-Up Studies, Humans, Iron analysis, Lipids analysis, Male, Middle Aged, Nicotinic Acids analysis, Nutritional Requirements, Physical Fitness, Proteins analysis, Riboflavin analysis, Thiamine analysis, Urination, Vitamin A analysis, Diet, Fruit
Published
1971

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