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Start Over Author "Charlton RW" Journal south african journal of medical sciences
8 results on '"Charlton RW"'

1. The mechanism of the inhibition of iron absorption by tea.

Author

Disler PB, Lynch SR, Torrance JD, Sayers MH, Bothwell TH, and Charlton RW

Subjects
Chemical Phenomena, Chemistry, Depression, Chemical, Hydrogen-Ion Concentration, Iron analysis, Molecular Weight, Tannins analysis, Tannins pharmacology, Intestinal Absorption drug effects, Iron metabolism, Tea
Abstract

Previous human studies have shown that drinking tea during meals significantly inhibits the absorption of both food iron and medicinal iron. This study provides evidence from experiments with rats that the tannins in the tea are responsible for the inhibition, probably by forming non-absorbable complexes with the iron within the intestinal lumen. The molar ratio of tannin: iron is dependent on the pH, being 1:1 at pH 2,0 2:1 at pH 5,5 and 3:1 at pH 8,0. Since tannins are present in many vegetable foods the formation of such complexes may be a factor in the poor availability for absorption of much food iron.

Published
1975

2. Storage iron in muscle.

Author

Torrance JD, Schmaman A, Lynch SR, Charlton RW, and Bothwell TH

Subjects
Chemical Phenomena, Chemistry, Humans, In Vitro Techniques, Iron, Liver, Muscles
Published
1965

4. Hepatic iron storage concentrations in the inhabitants of Papua New Guinea.

Author

Disler P, Charlton RW, Bothwell TH, and Kariks J

Subjects
Adolescent, Adult, Age Factors, Anemia, Hypochromic epidemiology, Autopsy, Cardiovascular Diseases metabolism, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Infections metabolism, Male, Neoplasms metabolism, New Guinea, Sex Factors, Uremia metabolism, Wounds and Injuries metabolism, Black or African American, Iron analysis, Liver analysis
Published
1973

5. Some aspects of calcium metabolism in normal and osteoporotic Bantu subjects with special reference to the effects of iron overload and ascorbic acid depletion.

Author

Lynch SR, Seftel HC, Wapnick AA, Charlton RW, and Bothwell TH

Subjects
Adult, Alcohol Drinking, Animals, Ascorbic Acid Deficiency complications, Black People, Calcium analysis, Calcium Chloride metabolism, Calcium Isotopes, Calcium Metabolism Disorders complications, Female, Guinea Pigs, Humans, Intestinal Absorption, Male, Middle Aged, Osteoporosis etiology, Rats, South Africa, Sweat analysis, Black or African American, Ascorbic Acid Deficiency metabolism, Calcium metabolism, Osteoporosis metabolism, Siderosis metabolism
Published
1970

7. Iron compounds in muscle.

Author

Clement N, Torrance JD, Bothwell TH, and Charlton RW

Subjects
Animals, Cattle, Chickens, Chromatography, Heme analysis, Heme metabolism, Intestinal Absorption, Iron analysis, Iron Isotopes, Male, Myoglobin analysis, Myoglobin metabolism, Rats, Spectrum Analysis, Fish Products analysis, Iron metabolism, Meat analysis, Muscles metabolism
Published
1972

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