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The aim of this paper is to explore the impact of information technology (IT) on organization including all elements that are integral part of organizational design through Star Model (Kates and Galbraith, 2007), and to show that IT has become an important strategic resource that provides a concentration of all relevant information for quality decision-making and integration of complex organization with the concept of “Big Data” (Manyika et al, 2011). In order to achieve the aim, research was performed in organization in the health sector which affects the quality of life and standard of living. TheIT impact on organizational design and through him on organizational effectiveness in the health care is visible and provide insight into the implications of information technology and opportunities for reasoning about matters that are the subject of research: whether and how information technology causes changes in the design of the organization; whether it affects all elements of design equally; on which elements has the most intense impact and why; whether and why employees and users of health services exhibit resistance to information technology; under what conditions can be reduced or completely eliminated the resistance of employees and users of health services?

The aim of this paper is to investigate the role of managers with leadership potentials in knowledge management within organization. This aim is further developed through the research questions: (1) Does leadership have important role in knowledge management? (2) Under which conditions leadership influences knowledge management and what is the direction of this influence? (3) Which elements of the leadership, skills and virtues of the leader, are important and what roles do they have in knowledge management? The paper is based on the field investigation, employing interviews and survey as the research techniques, on the random sample of Serbian companies.