1. The long-term impact of expansion sphincter pharyngoplasty treatment on blood pressure control and health-related quality of life in patients with obstructive sleep apnea and hypertension
- Author
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Si-Fan Gao, Hongting Hua, Dong Wang, Y H Liu, Jun Chen, Yun-Xia Ma, and Chao-Bing Gao
- Subjects
Adult ,Male ,medicine.medical_specialty ,Ambulatory blood pressure ,Neurology ,medicine.drug_class ,Diastole ,Obstetric Surgical Procedures ,Comorbidity ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Internal medicine ,Outcome Assessment, Health Care ,medicine ,Humans ,Antihypertensive drug ,Antihypertensive Agents ,Aged ,Sleep Apnea, Obstructive ,business.industry ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Obstructive sleep apnea ,Blood pressure ,medicine.anatomical_structure ,030228 respiratory system ,Otorhinolaryngology ,Hypertension ,Cardiology ,Quality of Life ,Sphincter ,Pharynx ,Female ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
To assess how expansion sphincter pharyngoplasty (ESP) impacts blood pressure (BP) and health-related quality of life (HRQOL) in hypertensive patients with obstructive sleep apnea (OSA). Patients were separated into two groups based upon whether or not they adhered to antihypertensive drug regimens. Patients underwent 24-h ambulatory BP monitoring before and at 6 months post-ESP, while clinical BP measurements and HRQOL questionnaires (SF-36) were conducted over the course of 24 months post-surgery. We enrolled 62 patients, with 25 and 37 in the medicated and non-medicated groups, respectively. Mean 24-h BP differed significantly, with systolic and diastolic BP (SBP and DBP) decreases of 5.3 mmHg and 2.5 mmHg, respectively (P
- Published
- 2020