6 results on '"Veauthier C"'
Search Results
2. Apnea characterization by means of suprasternal pressure, respiratory inductance plethysmography and oesophageal pressure: a comparative study
- Author
-
Glos, M., primary, Günther, A.C., additional, Sabil, A., additional, Schöbel, C., additional, Veauthier, C., additional, Fietze, I., additional, and Penzel, T., additional
- Published
- 2017
- Full Text
- View/download PDF
3. Barriers to therapy adherence in narcolepsy.
- Author
-
Finger BM, Bourke AM, Lammers GJ, Veauthier C, Yildizli M, Müller S, Triller A, and Kallweit U
- Subjects
- Humans, Female, Male, Adult, Surveys and Questionnaires, Middle Aged, Depression drug therapy, Narcolepsy drug therapy, Narcolepsy psychology, Medication Adherence psychology, Medication Adherence statistics & numerical data
- Abstract
Background: Treatment adherence (TA) in narcolepsy is a complex phenomenon influenced by various factors beyond patient-related aspects. The management of narcolepsy involves non-pharmacological and symptomatic pharmacological treatment. Factors such as chronic daytime sleepiness, cognitive deficits, psychiatric comorbidities and adverse effects of pharmacological treatment are aspects of narcolepsy that could undermine TA, impacting patients' ability or willingness to consistently follow treatment plans. The aim of this study was to identify the factors influencing TA in narcolepsy and to determine the most significant barriers to adherence., Methods: An online survey was conducted during the pandemic, assessing demographic and clinical data, medication usage, and adverse effects of treatment. Various questionnaires, such as the Adherence Barriers Questionnaire (ABQ) and Epworth Sleepiness Scale (ESS), were utilized. The ABQ identified patient-specific barriers to medication adherence, while the Patient Health Questionnaire (PHQ-9) assessed depressive symptoms., Results: We analyzed 243 narcolepsy patients (77 % female, mean age 35.7 ± 12.3 years) with 71 % having narcolepsy type 1 (NT1). The average ESS score was 16.4 (SD ± 3.7). Adherence barriers (AB) were identified in 89 % of patients (216/243) based on ABQ score. The most common barriers reported were "Forgetfulness" (77 %), "Depression" (57 %), and "Side effect-driven medication reduction/stopping behavior" (49 %). Approximately 72 % of patients reported side effects from their narcolepsy medication, leading to discontinuation in 78 % of cases. A moderate correlation was found between the severity of adherence barriers (ABQ score) and levels of depression (PHQ-9 score; rs = 0.412, p = 00.000), as well as ESS score (p = . 048). The results of this study may have been influenced by the pandemic situation., Conclusion: Adherence barriers are common (89 %) and diverse among people with narcolepsy. Many barriers are related to excessive daytime sleepiness (EDS), cognitive deficits or depressive symptoms, highlighting the importance of recognizing and addressing them for optimal TA. Medication side effects, especially occurring when polypharmacology is utilized, also significantly contribute to adherence challenges. Effective communication regarding therapy adherence and improved detection and management of EDS and depression are crucial for enhancing TA in narcolepsy patients., Competing Interests: Declaration of competing interest The authors declare no potential conflicts of interest., (Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
4. Complementary and alternative medicine use in narcolepsy.
- Author
-
Finger BM, Triller A, Bourke AM, Lammers GJ, Veauthier C, Yildizli M, and Kallweit U
- Subjects
- Humans, Surveys and Questionnaires, Emotions, Complementary Therapies, Narcolepsy drug therapy, Meditation
- Abstract
Background: Management of narcolepsy includes behavior strategies and symptomatic pharmacological treatment. In the general population, complementary and alternative medicine (CAM) use is common in Europe (30%), also in chronic neurological disorders (10-20%). The aim of our study was to evaluate frequency and characteristics of CAM use in German narcolepsy patients., Methods: Demographic, disease-related data frequency and impact of CAM use were assessed in an online survey. Commonly used CAM treatments were predetermined in a questionnaire based on the National Center for Complementary and Alternative Medicine and included the domains: (1) alternative medical systems; (2) biologically based therapies; (3) energy therapies; (4) mind-body interventions, and (5) manipulative and body-based therapies., Results: We analyzed data from 254 questionnaires. Fifteen percent of participants were at the time of survey administration using CAM for narcolepsy, and an additional 18% of participants reported past use. Among the 33% of CAM users, vitamins/trace elements (54%), homoeopathy (48%) and meditation (39%) were used most frequently. 54% of the users described CAM as helpful. CAM users more frequently described having side effects from their previous medication (p = 0.001), and stated more frequently not to comply with pharmacological treatment than non-CAM users (21% vs. 8%; p = 0.024)., Discussion: The use of CAM in narcolepsy patients is common. Our results indicate that many patients still feel the need to improve their symptoms, sleepiness and psychological well-being in particular. Frequent medication change, the experience of adverse events and low adherence to physician-recommended medication appears more frequent in CAM users. The impact of CAM however seems to be limited., Competing Interests: Declaration of competing interest The authors declare no potential conflicts of interest., (Copyright © 2023 Elsevier B.V. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
5. Hypnotic use and multiple sclerosis related fatigue: a forgotten confounder.
- Author
-
Veauthier C
- Subjects
- Female, Humans, Male, Fatigue diagnosis, Fatigue epidemiology, Hypnotics and Sedatives therapeutic use, Multiple Sclerosis complications, Sleep Wake Disorders drug therapy
- Published
- 2015
- Full Text
- View/download PDF
6. Sleep disorders in multiple sclerosis and their relationship to fatigue.
- Author
-
Veauthier C and Paul F
- Subjects
- Fatigue physiopathology, Humans, Multiple Sclerosis physiopathology, Nocturia physiopathology, Restless Legs Syndrome physiopathology, Sleep Wake Disorders physiopathology, Fatigue etiology, Multiple Sclerosis complications, Nocturia etiology, Restless Legs Syndrome complications, Sleep Wake Disorders complications
- Abstract
Treatment of multiple sclerosis (MS)-related fatigue is still a challenging task, given that no proven therapies exist and its mechanisms are not known. Our review highlights the relationship between MS-related fatigue and sleep disorders (SD). Although many studies suggest a higher overall prevalence of SD in MS, there are no valid and robust data to confirm this hypothesis until now except for restless legs syndrome (RLS): the prevalence of RLS in MS patients-especially in those with severe pyramidal and sensory disability-seems to be four times higher than in controls subjects. RLS is sometimes difficult to distinguish from spasticity and in case of doubt, probatory dopaminergic therapy or polysomnographic (PSG) investigations may be helpful. Nocturia may impact MS-related fatigue and should be considered. The treatment of underlying SD led to an improvement of MS-related fatigue. From a scientific point of view, SD should be examined in all studies investigating MS-related fatigue and be considered as a relevant confounder., (Copyright © 2013 Elsevier B.V. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.