1. Fe NPs and MWCNTs based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids
- Author
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Jing Wang, Hui Peng, Jianzhong Zhu, Lei Yu, Yiting Wang, and Xueying Liu
- Subjects
Microdialysis ,Analytical chemistry ,Nanoparticle ,02 engineering and technology ,Carbon nanotube ,01 natural sciences ,law.invention ,Magazine ,law ,Materials Chemistry ,Electrical and Electronic Engineering ,Instrumentation ,Flow injection analysis ,chemistry.chemical_classification ,Chromatography ,Chemistry ,010401 analytical chemistry ,Metals and Alloys ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Amperometry ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Amino acid ,Electrode ,0210 nano-technology - Abstract
An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. The electrode combined with Flow Injection Analysis (FIA) exhibits linear response in the concentration range of 0.1–12 μM and the sensitivity of 30.0 nA μM −1 for most of amino acids, confirming good complexation of amino acids (AAs) with Fe NPs on the modified electrode. The determination of 17 amino acids in the hypothalamus microdialysis fluids of guinea pigs, illustrates that it is a powerful tool to investigate physiology and pathology mechanisms.
- Published
- 2017