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3 results on '"Gaus, V."'

1. Manic/hypomanic symptoms and quality of life measures in patients with epilepsy

Author

Laura Collimedaglia, Francesco Monaco, Bettina Schmitz, R. Kretz, Regina Jauch, Roberto Cantello, Michele Viana, Andrea E. Cavanna, Marco Mula, Verena Gaus, Davide Barbagli, Mula, M, Jauch, R, Cavanna, A, Collimedaglia, L, Barbagli, D, Gaus, V, Kretz, R, Viana, M, Cantello, R, Monaco, F, and Schmitz, B

Subjects
Quality of life, Adult, Employment, Male, medicine.medical_specialty, Bipolar Disorder, Personality Inventory, Clinical Neurology, Comorbidity, Neuropsychological Tests, Severity of Illness Index, Epilepsy, Surveys and Questionnaires, medicine, Humans, In patient, Bipolar disorder, Psychiatry, Depression (differential diagnoses), Psychiatric Status Rating Scales, General Medicine, Hypomania, Middle Aged, medicine.disease, Mania, Neurology, Socioeconomic Factors, Female, Neurology (clinical), medicine.symptom, Psychology, Independent living, Clinical psychology
Abstract

Purpose Although several studies pointed out an association between depression and quality of life (QoL) of patients with epilepsy, data about manic/hypomanic symptoms (MHS) remain scanty. In this study, we sought to investigate their relationship with social and health-related QoL measures in patients with epilepsy. Methods Consecutive adult outpatients with epilepsy were assessed using the M.I.N.I. Plus version 5.0.0 and the QOLIE-31. Results Among 117 evaluated patients, 17 fulfilled DSM-IV criteria for manic/hypomanic episodes. Patients with MHS, as compared to those without, showed lower scores in emotional well-being, energy and fatigue, medication effects, social function and total QOLIE score. However, there was no between-groups difference in educational achievements, employment status, living situation, comorbid psychiatric disorders, history of suicide or abuse of illicit drugs. Conclusions MHS are associated with poor QoL measures in patients with epilepsy, though without differences in educational achievements, employment status and independent living.

Published
2009

2. Gender differences in depression, but not in anxiety in people with epilepsy.

Author

Gaus V, Kiep H, Holtkamp M, Burkert S, and Kendel F

Subjects
Adult, Anticonvulsants adverse effects, Anticonvulsants therapeutic use, Comorbidity, Epilepsy drug therapy, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Seizures drug therapy, Seizures epidemiology, Seizures psychology, Self Report, Sex Factors, Anxiety epidemiology, Depression epidemiology, Epilepsy epidemiology, Epilepsy psychology
Abstract

Purpose: Anxiety and depression are frequent comorbidities in people with epilepsy (PWE), but possible gender differences are often neglected. The aim of the present study was to analyze if men and women with epilepsy differ with regard to anxiety and depressive symptoms and to identify possible predictors., Methods: Adult consecutive PWE (N=302; 53% women) completed self-report questionnaires, including the depression module of the Patient Health Questionnaire (PHQ-9), the anxiety module of the Hospital Anxiety and Depression Scale (HADS-A) and the subscales "medication effects" and "seizure worry" of the Patient-weighted Quality of Life in Epilepsy Inventory-31-P (QOLIE-31-P)., Results: There was no gender difference in extent of anxiety (p=.532), which was mainly due to higher anxiety levels in men compared to the general population. The gender difference in depressive symptoms was significant (p=.009), with female patients being more affected. The most important predictors for anxiety and depressive symptoms were detrimental effects of medication (QOL medication effects) and of seizure worry (QOL seizure worry). Moreover, these predictors were more closely associated with anxiety and depressive symptoms in men., Conclusion: Future intervention studies could show whether providing more information about the illness and medication effects may improve anxiety and depression. Our results suggest that such interventions should be tailored to the different needs of men and women., (Copyright © 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.)

Published
2015
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3. Manic/hypomanic symptoms and quality of life measures in patients with epilepsy.

Author

Mula M, Jauch R, Cavanna A, Collimedaglia L, Barbagli D, Gaus V, Kretz R, Viana M, Cantello R, Monaco F, and Schmitz B

Subjects
Adult, Comorbidity, Employment, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Personality Inventory, Psychiatric Status Rating Scales, Severity of Illness Index, Socioeconomic Factors, Surveys and Questionnaires, Bipolar Disorder complications, Bipolar Disorder psychology, Epilepsy complications, Epilepsy psychology
Abstract

Purpose: Although several studies pointed out an association between depression and quality of life (QoL) of patients with epilepsy, data about manic/hypomanic symptoms (MHS) remain scanty. In this study, we sought to investigate their relationship with social and health-related QoL measures in patients with epilepsy., Methods: Consecutive adult outpatients with epilepsy were assessed using the M.I.N.I. Plus version 5.0.0 and the QOLIE-31., Results: Among 117 evaluated patients, 17 fulfilled DSM-IV criteria for manic/hypomanic episodes. Patients with MHS, as compared to those without, showed lower scores in emotional well-being, energy and fatigue, medication effects, social function and total QOLIE score. However, there was no between-groups difference in educational achievements, employment status, living situation, comorbid psychiatric disorders, history of suicide or abuse of illicit drugs., Conclusions: MHS are associated with poor QoL measures in patients with epilepsy, though without differences in educational achievements, employment status and independent living.

Published
2009
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