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Start Over Author "Yan, Dan" Journal scientific reports
12 results on '"Yan, Dan"'

5. Noninvasive scoring system for significant inflammation related to chronic hepatitis B

Author

Yan-Dan Ren, Li-Xin Jin, Kuangnan Fang, Jin-Shui Pan, Xiao-Fang Yu, Mei-Zhu Hong, Linglong Ye, Xiao-Bin Liu, and Ru-Mian Zhang

Subjects
Adult, Male, medicine.medical_specialty, Hepatitis B virus, Inflammation, Logistic regression, 01 natural sciences, Gastroenterology, Article, 010104 statistics & probability, 03 medical and health sciences, 0302 clinical medicine, Hepatitis B, Chronic, Antigen, Predictive Value of Tests, Internal medicine, medicine, Humans, Hepatitis B e Antigens, 0101 mathematics, Multidisciplinary, business.industry, Area under the curve, Hepatitis B, medicine.disease, Logistic Models, Liver, ROC Curve, Predictive value of tests, Host-Pathogen Interactions, 030211 gastroenterology & hepatology, Female, Liver function, medicine.symptom, Transient elastography, business, Biomarkers
Abstract

Although a liver stiffness measurement-based model can precisely predict significant intrahepatic inflammation, transient elastography is not commonly available in a primary care center. Additionally, high body mass index and bilirubinemia have notable effects on the accuracy of transient elastography. The present study aimed to create a noninvasive scoring system for the prediction of intrahepatic inflammatory activity related to chronic hepatitis B, without the aid of transient elastography. A total of 396 patients with chronic hepatitis B were enrolled in the present study. Liver biopsies were performed, liver histology was scored using the Scheuer scoring system, and serum markers and liver function were investigated. Inflammatory activity scoring models were constructed for both hepatitis B envelope antigen (+) and hepatitis B envelope antigen (−) patients. The sensitivity, specificity, positive predictive value, negative predictive value, and area under the curve were 86.00%, 84.80%, 62.32%, 95.39%, and 0.9219, respectively, in the hepatitis B envelope antigen (+) group and 91.89%, 89.86%, 70.83%, 97.64%, and 0.9691, respectively, in the hepatitis B envelope antigen (−) group. Significant inflammation related to chronic hepatitis B can be predicted with satisfactory accuracy by using our logistic regression-based scoring system.

Published
2017

7. Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues

Author

Gao, Yanyan, primary, Wang, Xinzheng, additional, Sang, Zhihong, additional, Li, Zongcheng, additional, Liu, Feng, additional, Mao, Jie, additional, Yan, Dan, additional, Zhao, Yongqiang, additional, Wang, Hongli, additional, Li, Ping, additional, Ying, Xiaomin, additional, Zhang, Xuemin, additional, He, Kun, additional, and Wang, Hongxia, additional

Published
2017
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10. Magnetic Resonance Imaging Revealed Splenic Targeting of Canine Parvovirus Capsid Protein VP2

Author

Ma, Yufei, primary, Wang, Haiming, additional, Yan, Dan, additional, Wei, Yanquan, additional, Cao, Yuhua, additional, Yi, Peiwei, additional, Zhang, Hailu, additional, Deng, Zongwu, additional, Dai, Jianwu, additional, Liu, Xiangtao, additional, Luo, Jianxun, additional, Zhang, Zhijun, additional, Sun, Shiqi, additional, and Guo, Huichen, additional

Published
2016
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11. Promotion of quality standard of herbal medicine by constituent removing and adding

Author

Yan, Dan, primary, Li, Junxian, additional, Xiong, Yin, additional, Zhang, Congen, additional, Luo, Jiaoyang, additional, Han, Yumei, additional, Wang, Ruiling, additional, Jin, Cheng, additional, Qian, Hong, additional, Li, Jiangyu, additional, Qiu, Lingling, additional, Peng, Cheng, additional, Lin, Yuling, additional, Song, Xueai, additional, and Xiao, Xiaohe, additional

Published
2014
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