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4 results on '"Levula, Mari"'

1. Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm – The Tampere Vascular Study

Author

Sulkava, Miska, primary, Raitoharju, Emma, additional, Mennander, Ari, additional, Levula, Mari, additional, Seppälä, Ilkka, additional, Lyytikäinen, Leo-Pekka, additional, Järvinen, Otso, additional, Illig, Thomas, additional, Klopp, Norman, additional, Mononen, Nina, additional, Laaksonen, Reijo, additional, Kähönen, Mika, additional, Oksala, Niku, additional, and Lehtimäki, Terho, additional

Published
2017
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2. Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques – Tampere Vascular Study

Author

Sulkava, Miska, primary, Raitoharju, Emma, additional, Levula, Mari, additional, Seppälä, Ilkka, additional, Lyytikäinen, Leo-Pekka, additional, Mennander, Ari, additional, Järvinen, Otso, additional, Zeitlin, Rainer, additional, Salenius, Juha-Pekka, additional, Illig, Thomas, additional, Klopp, Norman, additional, Mononen, Nina, additional, Laaksonen, Reijo, additional, Kähönen, Mika, additional, Oksala, Niku, additional, and Lehtimäki, Terho, additional

Published
2017
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3. Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

Author

Fan, Yue-Mei, primary, Hernesniemi, Jussi, additional, Oksala, Niku, additional, Levula, Mari, additional, Raitoharju, Emma, additional, Collings, Auni, additional, Hutri-Kähönen, Nina, additional, Juonala, Markus, additional, Marniemi, Jukka, additional, Lyytikäinen, Leo-Pekka, additional, Seppälä, Ilkka, additional, Mennander, Ari, additional, Tarkka, Matti, additional, Kangas, Antti J., additional, Soininen, Pasi, additional, Salenius, Juha Pekka, additional, Klopp, Norman, additional, Illig, Thomas, additional, Laitinen, Tomi, additional, Ala-Korpela, Mika, additional, Laaksonen, Reijo, additional, Viikari, Jorma, additional, Kähönen, Mika, additional, Raitakari, Olli T., additional, and Lehtimäki, Terho, additional

Published
2014
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4. Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque.

Author

Yue-Mei Fan, Hernesniemi, Jussi, Oksala, Niku, Levula, Mari, Raitoharju, Emma, Collings, Auni, Hutri-Kähönen, Nina, Juonala, Markus, Marniemi, Jukka, Lyytikäinen, Leo-Pekka, Seppälä, Ilkka, Mennander, Ari, Tarkka, Matti, Kangas, Antti J., Soininen, Pasi, Salenius, Juha Pekka, Klopp, Norman, Illig, Thomas, Laitinen, Tomi, and Ala-Korpela, Mika

Subjects
TRANSCRIPTION factors, LIPOPROTEINS, METABOLISM, ATHEROSCLEROTIC plaque, ATHEROSCLEROSIS, LIPIDS, MESSENGER RNA
Abstract

Upstream transcription factor 1 (USF1) allelic variants significantly influence future risk of cardiovascular disease and overall mortality in females. We investigated sex-specific effects of USF1 gene allelic variants on serum indices of lipoprotein metabolism, early markers of asymptomatic atherosclerosis and their changes during six years of follow-up. In addition, we investigated the cis-regulatory role of these USF1 variants in artery wall tissues in Caucasians. In the Cardiovascular Risk in Young Finns Study, 1,608 participants (56% women, aged 31.9 ± 4.9) with lipids and cIMT data were included. For functional study, whole genome mRNA expression profiling was performed in 91 histologically classified atherosclerotic samples. In females, serum total, LDL cholesterol and apoB levels increased gradually according to USF1 rs2516839 genotypes TT

Published
2014
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