Search

Your search keyword '"Jacobs, Reinhilde"' showing total 17 results
Start Over Author "Jacobs, Reinhilde" Journal scientific reports
17 results on '"Jacobs, Reinhilde"'

15. Halve the dose while maintaining image quality in paediatric Cone Beam CT

Author

Oenning, Anne Caroline, Pauwels, Ruben, Stratis, Andreas, Vasconcelos, Karla De Faria, Tijskens, Elisabeth, De Grauwe, Annelore, Jacobs, Reinhilde, Salmon, Benjamin, Chaussain, Catherine, Bosmans, Hilde, Bogaerts, Ria, Politis, Constantinus, Nicolielo, Laura, Zhang, Guozhi, Vranckx, Myrthel, Ockerman, Anna, Baatout, Sarah, Bemans, Niels, Moreels, Marjan, Hedesiu, Mihaela, Virag, Pirsoka, Baciut, Mihaela, Marcu, Maria, Almasan, Oana, Roman, Raluca, Barbur, Ioan, Dinu, Cristian, Rotaru, Horatiu, Hurubeanu, Lucia, Istouan, Vlad, Lucaciu, Ondine, Leucuta, Daniel, Crisan, Bogdan, Bogdan, Loredana, Candea, Ciprian, Bran, Simion, and Baciut, Grigore

Subjects
0301 basic medicine, Image quality, lcsh:Medicine, Test object, computer.software_genre, Radiation Dosage, Effective dose (radiation), Article, 03 medical and health sciences, 0302 clinical medicine, Voxel, Image Interpretation, Computer-Assisted, Dimitra research group, Maxilla, Medicine, Humans, Child, lcsh:Science, Voxel size, Cone beam ct, Multidisciplinary, business.industry, Phantoms, Imaging, lcsh:R, Clinical performance, Cone-Beam Computed Tomography, Publisher Correction, Confidence interval, 030104 developmental biology, lcsh:Q, Nuclear medicine, business, computer, Monte Carlo Method, Tooth, 030217 neurology & neurosurgery
Abstract

Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of the risks of the low-dose radiation exposures. The aim of this work was to investigate the clinical performance of different CBCT acquisition protocols towards the optimization of paediatric exposures. Custom-made anthropomorphic phantoms were scanned using a CBCT unit in six protocols. CT slices were blinded, randomized and presented to three observers, who scored the image quality using a 4-point scale along with their level of confidence. Sharpness level was also measured using a test object containing an air/PMMA e,dge. The effective dose was calculated by means of a customized Monte Carlo (MC) framework using previously validated paediatric voxels models. The results have shown that the protocols set with smaller voxel size (180 µm), even when decreasing exposure parameters (kVp and mAs), showed high image quality scores and increased sharpness. The MC analysis showed a gradual decrease in effective dose when exposures parameters were reduced, with an emphasis on an average reduction of 45% for the protocol that combined 70 kVp, 16 mAs and 180 µm voxel size. In contrast, both "ultra-low dose" protocols that combined a larger voxel size (400 µm) with lower mAs (7.4 mAs) demonstrated the lowest scores with high levels of confidence unsuitable for an anatomical approach. In conclusion, a significant decrease in the effective dose can be achieved while maintaining the image quality required for paediatric CBCT. ispartof: SCIENTIFIC REPORTS vol:9 issue:1 ispartof: location:England status: published

Published
2019

16. Quantification of DNA Double Strand Breaks and Oxidation Response in Children and Adults Undergoing Dental CBCT Scan.

Author

Belmans, Niels, Gilles, Liese, Vermeesen, Randy, Virag, Piroska, Hedesiu, Mihaela, Salmon, Benjamin, Baatout, Sarah, Lucas, Stéphane, Lambrichts, Ivo, Jacobs, Reinhilde, Moreels, Marjan, DIMITRA Research Group, Oenning, A. C., Chaussain, C., Lefevre, C., Baciut, M., Marcu, M., Almasan, O., Roman, R., and Barbur, I.

Subjects
DOUBLE-strand DNA breaks, CONE beam computed tomography, IONIZING radiation, RADIATION protection, DIAGNOSTIC imaging, OXIDANT status
Abstract

Assessing the possible biological effects of exposure to low doses of ionizing radiation (IR) is one of the prime challenges in radiation protection, especially in medical imaging. Today, radiobiological data on cone beam CT (CBCT) related biological effects are scarce. In children and adults, the induction of DNA double strand breaks (DSBs) in buccal mucosa cells and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) and antioxidant capacity in saliva samples after CBCT examination were examined. No DNA DSBs induction was observed in children nor adults. In children only, an increase in 8-oxo-dG levels was observed 30 minutes after CBCT. At the same time an increase in antioxidant capacity was observed in children, whereas a decrease was observed in adults. Our data indicate that children and adults react differently to IR doses associated with CBCT. Fully understanding these differences could lead to an optimal use of CBCT in different age categories as well as improved radiation protection guidelines. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results