1. Novel Method for Neuronal Nanosurgical Connection
- Author
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Nir Katchinskiy, Abdulhakem Y. Elezzabi, Helly Goez, Indrani Dutta, and Roseline Godbout
- Subjects
0301 basic medicine ,Pathology ,medicine.medical_specialty ,Cell type ,Cell Survival ,Inflammation ,Biology ,Cellular viability ,Article ,Cell Line ,Cell Physiological Phenomena ,03 medical and health sciences ,Mice ,0302 clinical medicine ,Immune system ,Laser application ,medicine ,Animals ,Axon ,Neurons ,Multidisciplinary ,Tissue Engineering ,Lasers ,030104 developmental biology ,medicine.anatomical_structure ,Nanomedicine ,nervous system ,medicine.symptom ,Neuronal soma ,Neuroscience ,030217 neurology & neurosurgery ,Function (biology) - Abstract
Neuronal injury may cause an irreversible damage to cellular, organ and organism function. While preventing neural injury is ideal, it is not always possible. There are multiple etiologies for neuronal injury including trauma, infection, inflammation, immune mediated disorders, toxins and hereditary conditions. We describe a novel laser application, utilizing femtosecond laser pulses, in order to connect neuronal axon to neuronal soma. We were able to maintain cellular viability and demonstrate that this technique is universal as it is applicable to multiple cell types and media.
- Published
- 2016
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