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9 results on '"Indolfi, Ciro"'

8. Hindlimb Ischemia Impairs Endothelial Recovery and Increases Neointimal Proliferation in the Carotid Artery

Author

Sorrentino, Sabato, primary, Iaconetti, Claudio, additional, De Rosa, Salvatore, additional, Polimeni, Alberto, additional, Sabatino, Jolanda, additional, Gareri, Clarice, additional, Passafaro, Francesco, additional, Mancuso, Teresa, additional, Tammè, Laura, additional, Mignogna, Chiara, additional, Camastra, Caterina, additional, Esposito, Giovanni, additional, Curcio, Antonio, additional, Torella, Daniele, additional, and Indolfi, Ciro, additional

Published
2018
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9. Low-dose anticoagulation after isolated mechanical aortic valve replacement with Liva Nova Bicarbon prosthesis: A post hoc analysis of LOWERING-IT Trial

Author

Paolo Chiodini, Ciro Indolfi, Cristiano Amarelli, Gianpaolo Romano, Daniele Torella, Luca Salvatore De Santo, Michele Torella, Iolanda Aquila, Alessandro Della Corte, Ester Della Ratta, Marisa De Feo, Torella, Michele, Aquila, Iolanda, Chiodini, Paolo, Amarelli, Cristiano, Romano, Gianpaolo, Elena Della Ratta, Ester, DE FEO, Marisa, DELLA CORTE, Alessandro, Indolfi, Ciro, Torella, Daniele, and DE SANTO, Luca Salvatore

Subjects
Male, medicine.medical_specialty, endocrine system, medicine.medical_treatment, Prosthesis Implantation, lcsh:Medicine, 030204 cardiovascular system & hematology, Prosthesis, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Thromboembolism, health services administration, Post-hoc analysis, medicine, Humans, heterocyclic compounds, cardiovascular diseases, lcsh:Science, Mechanical Phenomena, Multidisciplinary, Dose-Response Relationship, Drug, business.industry, Low dose, fungi, lcsh:R, Anticoagulants, Mechanical Aortic Valve, Middle Aged, medicine.disease, Thrombosis, Surgery, 030228 respiratory system, Aortic Valve, Heart Valve Prosthesis, Feasibility Studies, Population study, Female, lcsh:Q, Safety, business
Abstract

Introduction: Thromboembolic complications are due to a complex interplay between patients’ characteristics, device features and anticoagulation intensity. Subtle design and material differences in available prostheses imply different susceptibility to thrombosis. This post hoc sub analysis of the LOWERING-IT database tested the safety and feasibility of a low-level oral anticoagulant regime in low-risk patients with aortic LivaNova prosthetic valve replacement. Methods: Study population included 148 patients randomized to LOW-INR group, and 144 patients randomized to CONVENTIONAL-INR group. The non inferiority of thromboembolic events between LOW-INR and CONVENTIONAL-INR groups was tested. Results: The two groups were well matched. Cumulative follow-up reached 1,545 patient/years. The mean INR was 1.91 ± 0.23 in the LOW-INR group, and 2.59 ± 0.26 in the CONVENTIONAL-INR group (P

Published
2018

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