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Start Over Author "Ding, Xin" Journal scientific reports
17 results on '"Ding, Xin"'

9. Time-Course Changes in Urine Metabolic Profiles of Rats Following 90-Day Exposure to Propoxur

Author

Hui-Ping Wang, Yu-Jie Liang, Yi-Jun Wu, Pan Wang, Ding-Xin Long, and Ying-Jian Sun

Subjects
0301 basic medicine, Male, Taurine, Insecticides, Time Factors, Proton Magnetic Resonance Spectroscopy, Succinic Acid, Physiology, lcsh:Medicine, Administration, Oral, Urine, Propoxur, Citric Acid, Article, 03 medical and health sciences, chemistry.chemical_compound, Methylamines, 0302 clinical medicine, Animal physiology, Medicine, Animals, Metabolomics, Rats, Wistar, lcsh:Science, Cholinesterase, Creatinine, Multidisciplinary, biology, business.industry, lcsh:R, Neurotoxicity, Diagnostic markers, medicine.disease, Acute toxicity, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Toxicity, biology.protein, Metabolome, lcsh:Q, business, Biomarkers, Dimethylamines
Abstract

As a major kind of carbamate insecticide, propoxur plays an important role in agriculture, veterinary medicine, and public health. The acute toxicity of propoxur is mainly neurotoxicity due to the inhibition of cholinesterase. However, little is known regarding the toxicity of propoxur upon long-term exposure at low dose. In this study, Wistar rats were orally administrated with low dose (4.25 mg/kg body weight/day) for consecutive 90 days. And the urine samples in rats treated with propoxur for 30, 60, and 90 days were collected and analyzed by employing 1H NMR-based metabolomics approach. We found that propoxur caused significant changes in the urine metabolites, including taurine, creatinine, citrate, succinate, dimethylamine, and trimethylamine-N-oxide. And the alteration of the metabolites was getting more difference compared with that of the control as the exposure time extending. The present study not only indicated that the changed metabolites could be used as biomarkers of propoxur-induced toxicity but also suggested that the time-course alteration of the urine metabolomic profiles could reflect the progressive development of the toxicity following propoxur exposure.

Published
2019

13. An epithelial-to-mesenchymal transition-inducing potential of granulocyte macrophage colony-stimulating factor in colon cancer

Author

Chen, Yaqiong, primary, Zhao, Zhi, additional, Chen, Yu, additional, Lv, Zhonglin, additional, Ding, Xin, additional, Wang, Renxi, additional, Xiao, He, additional, Hou, Chunmei, additional, Shen, Beifen, additional, Feng, Jiannan, additional, Guo, Renfeng, additional, Li, Yan, additional, Peng, Hui, additional, Han, Gencheng, additional, and Chen, Guojiang, additional

Published
2017
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14. Active KTaO3 hybrid terahertz metamaterial

Author

Wu, Liang, primary, Liu, Jinglong, additional, Li, Hui, additional, Ding, Chunfeng, additional, Xu, Ningning, additional, Zhao, Xiaolei, additional, Xu, Zongcheng, additional, Sheng, Quan, additional, Yao, Jianquan, additional, Li, Jining, additional, Ding, Xin, additional, and Zhang, Weili, additional

Published
2017
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17. Active KTaO 3 hybrid terahertz metamaterial.

Author

Wu L, Liu J, Li H, Ding C, Xu N, Zhao X, Xu Z, Sheng Q, Yao J, Li J, Ding X, and Zhang W

Abstract

The dielectric properties of an active KTaO 3 hybrid metamaterial structure and its tunability under external electric fields are investigated at room temperature by means of terahertz time-domain spectroscopy. Application of the electric field leads to an appreciable tuning of the dielectric loss, which is up to 17%. Meanwhile, the refractive index also changes appreciably. These findings are attributed to the internal space charge field in the crystal caused by the excited free carriers.

Published
2017
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