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Your search keyword '"Barnes, Kayla G."' showing total 4 results
Start Over Author "Barnes, Kayla G." Journal scientific reports
4 results on '"Barnes, Kayla G."'

1. Field evaluation of a Pan-Lassa rapid diagnostic test during the 2018 Nigerian Lassa fever outbreak

Author

Boisen, Matthew L., Uyigue, Eghosa, Aiyepada, John, Siddle, Katherine J., Oestereich, Lisa, Nelson, Diana K. S., Bush, Duane J., Rowland, Megan M., Heinrich, Megan L., Eromon, Philomena, Kayode, Adeyemi T., Odia, Ikponmwosa, Adomeh, Donatus I., Muoebonam, Ekene B., Akhilomen, Patience, Okonofua, Grace, Osiemi, Blessing, Omoregie, Omigie, Airende, Michael, Agbukor, Jacqueline, Ehikhametalor, Solomon, Aire, Chris Okafi, Duraffour, Sophie, Pahlmann, Meike, Böhm, Wiebke, Barnes, Kayla G., Mehta, Samar, Momoh, Mambu, Sandi, John Demby, Goba, Augustine, Folarin, Onikepe A., Ogbaini-Emovan, Ephraim, Asogun, Danny A., Tobin, Ekaete A., Akpede, George O., Okogbenin, Sylvanus A., Okokhere, Peter O., Grant, Donald S., Schieffelin, John S., Sabeti, Pardis C., Günther, Stephan, Happi, Christian T., Branco, Luis M., and Garry, Robert F.

Published
2020
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2. Acute rotavirus infection is associated with the induction of circulating memory CD4+ T cell subsets

Author

Malamba-Banda, Chikondi, primary, Mhango, Chimwemwe, additional, Benedicto-Matambo, Prisca, additional, Mandolo, Jonathan J., additional, Chinyama, End, additional, Kumwenda, Orpha, additional, Barnes, Kayla G., additional, Cunliffe, Nigel A., additional, Iturriza-Gomara, Miren, additional, Jambo, Kondwani C., additional, and Jere, Khuzwayo C., additional

Published
2023
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3. Acute rotavirus infection is associated with the induction of circulating memory CD4+ T cell subsets.

Author

Malamba-Banda, Chikondi, Mhango, Chimwemwe, Benedicto-Matambo, Prisca, Mandolo, Jonathan J., Chinyama, End, Kumwenda, Orpha, Barnes, Kayla G., Cunliffe, Nigel A., Iturriza-Gomara, Miren, Jambo, Kondwani C., and Jere, Khuzwayo C.

Subjects
ROTAVIRUS diseases, T cells, IMMUNOLOGIC memory, T helper cells, SYMPTOMS, CHILD development
Abstract

Strong CD4+ T cell-mediated immune protection following rotavirus infection has been observed in animal models, but its relevance in humans remains unclear. Here, we characterized acute and convalescent CD4+ T cell responses in children who were hospitalized with rotavirus-positive and rotavirus-negative diarrhoea in Blantyre, Malawi. Children presenting with laboratory-confirmed rotavirus infection had higher proportions of effector and central memory T helper 2 cells during acute infection i.e., at disease presentation compared to convalescence, 28 days post-infection defined by a follow-up 28 days after acute infection. However, circulating cytokine-producing (IFN-γ and/or TNF-α) rotavirus-specific VP6-specific CD4+ T cells were rarely detectable in children with rotavirus infection at both acute and convalescent stages. Moreover, following whole blood mitogenic stimulation, the responding CD4+ T cells were predominantly non-cytokine producers of IFN-γ and/or TNF-α. Our findings demonstrate limited induction of anti-viral IFN-γ and/or TNF-α-producing CD4+ T cells in rotavirus-vaccinated Malawian children following the development of laboratory-confirmed rotavirus infection. [ABSTRACT FROM AUTHOR]

Published
2023
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4. Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever

Author

Boisen, Matthew L., primary, Hartnett, Jessica N., additional, Shaffer, Jeffrey G., additional, Goba, Augustine, additional, Momoh, Mambu, additional, Sandi, John Demby, additional, Fullah, Mohamed, additional, Nelson, Diana K. S., additional, Bush, Duane J., additional, Rowland, Megan M., additional, Heinrich, Megan L., additional, Koval, Anatoliy P., additional, Cross, Robert W., additional, Barnes, Kayla G., additional, Lachenauer, Anna E., additional, Lin, Aaron E., additional, Nekoui, Mahan, additional, Kotliar, Dylan, additional, Winnicki, Sarah M., additional, Siddle, Katherine J., additional, Gbakie, Michael, additional, Fonnie, Mbalu, additional, Koroma, Veronica J., additional, Kanneh, Lansana, additional, Kulakosky, Peter C., additional, Hastie, Kathryn M., additional, Wilson, Russell B., additional, Andersen, Kristian G., additional, Folarin, Onikepe O., additional, Happi, Christian T., additional, Sabeti, Pardis C., additional, Geisbert, Thomas W., additional, Saphire, Erica Ollmann, additional, Khan, S. Humarr, additional, Grant, Donald S., additional, Schieffelin, John S., additional, Branco, Luis M., additional, and Garry, Robert F., additional

Published
2018
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