251. Blood flow disturbances in the central retinal artery in patients with bilateral optic disc drusen
- Author
-
Andrzej Ustymowicz and Iwona Obuchowska
- Subjects
Adult ,Male ,Central retinal artery ,medicine.medical_specialty ,genetic structures ,Retinal Artery ,Hemodynamics ,lcsh:Medicine ,Diseases ,Drusen ,Article ,03 medical and health sciences ,0302 clinical medicine ,medicine.artery ,Internal medicine ,mental disorders ,medicine ,Humans ,In patient ,Prospective Studies ,Ultrasonography, Doppler, Color ,Prospective cohort study ,lcsh:Science ,Multidisciplinary ,business.industry ,Optic Disk Drusen ,lcsh:R ,Blood flow ,Middle Aged ,medicine.disease ,Prognosis ,Optic disc drusen ,Stenosis ,Regional Blood Flow ,Case-Control Studies ,030221 ophthalmology & optometry ,Cardiology ,Female ,lcsh:Q ,business ,030217 neurology & neurosurgery ,Blood Flow Velocity ,Follow-Up Studies ,Neuroscience - Abstract
To evaluate retrobulbar hemodynamics in patients with optic disc drusen (ODD) by color Doppler imaging. A prospective study included 52 patients with bilateral ODD and 50 age-matched controls. Blood flow in the central retinal artery (CRA) in both eyes was evaluated. Peak-systolic velocity (PSV), end-diastolic velocity (EDV), and the resistivity index (RI) were measured. Mean values of the blood flow Doppler parameters were compared between the patients with ODD and the controls. Both PSV and EDV in the CRA were significantly lower in patients with ODD than in the controls (p p p = 0.05 and p = 0.03, respectively). Arterial hypertension, cigarette smoking and location of ODD in the left or right eye did not exert a significant effect on the blood flow in the CRA. Blood flow in the CRA is considerably disturbed in patients with ODD. This disturbance might result from mechanical stenosis of the vascular wall caused by the drusen. Color Doppler ultrasound is a useful method in the assessment of retrobulbar hemodynamics in ODD.
- Published
- 2020