1. Aqueous multiphoton lithography with multifunctional silk-centred bio-resists.
- Author
-
Sun, Yun-Lu, Li, Qi, Sun, Si-Ming, Huang, Jing-Chun, Zheng, Bo-Yuan, Chen, Qi-Dai, Shao, Zheng-Zhong, and Sun, Hong-Bo
- Subjects
SILK ,LITHOGRAPHY ,AQUEOUS solutions ,MULTIPHOTON processes ,FEMTOSECOND lasers ,SILK fibroin - Abstract
Silk and silk fibroin, the biomaterial from nature, nowadays are being widely utilized in many cutting-edge micro/nanodevices/systems via advanced micro/nanofabrication techniques. Herein, for the first time to our knowledge, we report aqueous multiphoton lithography of diversiform-regenerated-silk-fibroin-centric inks using noncontact and maskless femtosecond laser direct writing (FsLDW). Initially, silk fibroin was FsLDW-crosslinked into arbitrary two/three-dimensional micro/nanostructures with good elastic properties merely using proper photosensitizers. More interestingly, silk/metal composite micro/nanodevices with multidimension-controllable metal content can be FsLDW-customized through laser-induced simultaneous fibroin oxidation/crosslinking and metal photoreduction using the simplest silk/Ag
+ or silk/[AuCl4 ]− aqueous resists. Noticeably, during FsLDW, fibroin functions as biological reductant and matrix, while metal ions act as the oxidant. A FsLDW-fabricated prototyping silk/Ag microelectrode exhibited 104 -Ω−1 m−1 -scale adjustable electric conductivity. This work not only provides a powerful development to silk micro/nanoprocessing techniques but also creates a novel way to fabricate multifunctional metal/biomacromolecule complex micro/nanodevices for applications such as micro/nanoscale mechanical and electrical bioengineering and biosystems. [ABSTRACT FROM AUTHOR]- Published
- 2015
- Full Text
- View/download PDF