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The article offers information on a live chat on the benefits and risks of the National Science Advisory Board for Biosecurity (NSABB) recommendation on the H5N1 report, an avian flu paper which may trigger a pandemic, including the possibility of being utilized by bioterrorists.

The article reports on the decision of the U.S. National Science Advisory Board for Biosecurity to drop the variola amendment, a law that bans the synthesis of the smallpox virus in the U.S. The amendment was enacted by the U.S. Congress on December 17, 2004. The definition of smallpox virus according to the amendment is revealed. Complaints of researchers on the definition of the virus in the law are also raised.

Reports on the move made by the U.S. National Science Advisory Board for Biosecurity to develop safeguards against the wrongful application of life sciences research. Standard for identifying research that might have potential for misuse; Effort of the board to create implementing guidelines; Factors required to implement the guidelines.