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Salivary gland adenoma was linked to CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions. "Pleomorphic salivary gland adenomas are characterized by recurrent chromosome rearrangements of 8q 12, leading to activation of the PLAGI [...]

The susceptibility of Polish patients to adrenocortical cancer could be linked to the TP53 codon 72 polymorphism. According to recent research published in the journal Oncology Reports, "The TP53 polymorphism [...]

Colorectal adenoma genesis could be linked to epithelial and stromal genetic instability. "Previously, we indicated that stromal genetic instability might contribute to tumorigenesis of both sporadic and ulcerative colitis associated [...]

Colorectal adenoma screening might be warranted in APC I1307K polymorphism carriers. "The probability of colorectal cancer is moderately increased among carriers of the APC I1307K polymorphism. However, it is not [...]

A novel loss-of-function deletion in the sodium/iodide symporter (NIS) gene was found in thyroid adenoma. "The NIS actively transports iodide into thyrocytes. However, in thyroid carcinoma, down-regulated or mis-targeted NIS [...]

Gene methylation may play an important role in adenoma recurrence. According to recent research from the United States, "Hypermethylation of tumor suppressor and other regulatory genes is thought to play [...]

The PPARgamma Pro12Ala polymorphism may help protect against colorectal adenoma. "Peroxisome proliferator-activated receptor gamma (PPARgamma), a member of the nuclear hormone receptor superfamily initially shown to be a key regulator [...]

WNT and cyclooxygenase(COX)-2 cross-talk might accelerate adenoma growth in mice. "Both Wnt and COX-2 pathways are activated in most sporadic and familial colorectal cancers, especially in those with chromosomal instability. [...]