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9 results on '"Stan J"'

1. CRISPR-Cas : Adapting to change

Author

Jackson, Simon A., McKenzie, Rebecca E., Fagerlund, Robert D., Kieper, Sebastian N., Fineran, Peter C., and Brouns, Stan J. J.

Published
2017

3. Craspase is a CRISPR RNA-guided, RNA-activated protease

Author

Hu, Chunyi, primary, van Beljouw, Sam P. B., additional, Nam, Ki Hyun, additional, Schuler, Gabriel, additional, Ding, Fran, additional, Cui, Yanru, additional, Rodríguez-Molina, Alicia, additional, Haagsma, Anna C., additional, Valk, Menno, additional, Pabst, Martin, additional, Brouns, Stan J. J., additional, and Ke, Ailong, additional

Published
2022
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8. Sprites, ELF transients, and positive ground strokes

Author

Boccippio, Dennis J., Williams, Earle R., Heckman, Stan J., Lyons, Walter A., Baker, Ian T., and Boldi, Robert

Subjects
ELF electromagnetic fields -- Research, Atmospheric electricity -- Research, Mesosphere -- Research, Science and technology, Research
Abstract

In two summertime mesoscale convective systems (MCSs), mesospheric optical sprite phenomena were often coincident with both large-amplitude positive cloud-to-ground lightning and transient Schumann resonance excitations of the entire Earth-ionosphere cavity. These observations, together with earlier studies of MCS electrification, suggest that sprites are triggered when the rapid removal of large quantities of positive charge from an areally extensive charge layer stresses the mesosphere to dielectric breakdown., 'Red sprites' are mesospheric, striated glows that typically recur at intervals of several minutes over mature and dissipating organized convection (1-3). They have recently been documented over the stratiform regions [...]

Published
1995

9. A Swiss Army Knife of Immunity

Author

Stan J. J. Brouns

Subjects
Genetics, chemistry.chemical_compound, Multidisciplinary, Plasmid, chemistry, Effector, Cas9, Extrachromosomal DNA, CRISPR, Antitoxin, Biology, Acquired immune system, DNA
Abstract

Selfish genetic elements are more than a daily nuisance in the life of prokaryotes. Whereas viruses can multiply by reprogramming host cells, or integrate in the host genome as “stowaways,” conjugative plasmids (transferrable extrachromosomal DNA) make cells addicted to plasmid-encoded antitoxin factors, thus preventing their disposal. Bacteria and archaea defend themselves against these invasive elements using an adaptive immune system based on clustered regularly interspaced short palindromic repeats (CRISPRs). On page 816 in this issue, Jinek et al. ( 1 ) show how the CRISPR effector enzyme Cas9 from bacteria is directed not by one, but two small RNAs to cleave invader DNA.

Published
2012
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