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Your search keyword '"Gregory D. Schuler"' showing total 2 results
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2 results on '"Gregory D. Schuler"'

1. A Gene Map of the Human Genome

Author

Christopher Mader, B. B. Birren, Jean Morissette, C. Sanders, K. Swanson, Xiao-Yu Wu, Thomas J. Hudson, Mark S. Boguski, A. Maratukulam, Midori A. Harris, L. Green, S. Hussain, C. East, Robert E. White, Andrew A. Hicks, K. R. Iorio, Andrew B. Castle, W.-L. Sun, Paul Harrison, Simone Duprat, Kate Rice, Eric S. Lander, X. She, Shanti M. Perkins, Ammon B. Peck, Mina Sandusky, John Quackenbush, L. Hui, David Bentley, K. B. McKusick, Anindya Dehejia, Gregory D. Schuler, Gabor Gyapay, T. Dibling, C M Clee, Amita Aggarwal, James R. Hudson, R. Torres, Eva Bajorek, Peter N. Goodfellow, Mark Piercy, Mark Raymond Adams, Jun Fan, Cheryl Phillips, Elizabeth A. Stewart, Nicole Y. Fang, N. Drouot, Ian Dunham, Donna K. Slonim, Mihael H. Polymeropoulos, N. Nomura, Andrew J. Mungall, K. Ishikawa, E. Holloway, J. Ma, P. J. R. Day, N. Seki, S. Bentolila, Jean Weissenbach, P. Rodriguez-Tomé, Adam Butler, Sid Cowles, Angela M. Chu, Karin Schmitt, R. Houlgatte, Panos Deloukas, Tim Reif, Michael R. James, C. Louis-Dit-Sully, S. Voyticky, P. Tabar, David R. Cox, A. MacGilvery, David C. Page, Carol Soderlund, C A Edwards, S A Ranby, Nicole A.R. Walter, Douglas Vollrath, T. E. Wilmer, Lincoln Stein, H. C. Nusbaum, Takahiro Nagase, Tara C. Matise, T. Thangarajah, Susan E. Ide, Fawn Qin, Richard M. Myers, Steve Rozen, Jacques S. Beckmann, Richard Berry, James M. Sikela, Charles Auffray, Shannon T. Brady, Cécile Fizames, Christine Garrett, David Hadley, Delphine Muselet, Nathalie Vega-Czarny, Rhonda Brandon, Wha‐Young Lee, N. Chiannilkulchai, J. C. Venter, and James Silva

Subjects
Sequence-tagged site, Yeast artificial chromosome, Genetics, Expressed sequence tag, Multidisciplinary, Gene map, Gene mapping, Human genome, Computational biology, Genome project, Biology, Genome
Abstract

The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. An international consortium was organized to develop and map gene-based sequence tagged site markers on a set of two radiation hybrid panels and a yeast artificial chromosome library. More than 16,000 human genes have been mapped relative to a framework map that contains about 1000 polymorphic genetic markers. The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease. The integrated resource is available through a site on the World Wide Web at http://www.ncbi.nlm.nih.gov/SCIENCE96/.

Published
1996
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2. A Physical Map of 30,000 Human Genes

Author

Steve Rozen, N. Chiannilkulchai, James R. Hudson, L. D. Stein, D. Muselet, James M. Sikela, Caleb Webber, Charles Auffray, M. R. James, R. Staples, B. B. Birren, M.-T. Bihoreau, Gregory D. Schuler, A. Peck, H. C. Nusbaum, C. Louis-Dit-Sully, L. Hui, Jianpeng Ma, S. Duprat, N. Nomura, N. Vega-Czarny, J. Morissette, A. B. Castle, G. Gyapay, E. Holloway, Paul Harrison, P. J. R. Day, Jacques S. Beckmann, J. Browne, A. Mendis, Eric S. Lander, Thomas J. Hudson, Richard M. Myers, Philip Lijnzaad, Donna K. Slonim, S. Bentolila, D. R. Bentley, Panos Deloukas, Mark S. Boguski, Jean Weissenbach, C. Fizames, T. Thangarajah, E. A. Stewart, Marc A. Suchard, N. Drouot, E. M. Beasley, J.H. Miller, C. Clee, S. Gelling, K. B. McKusick, R. Hocking, D. Simon, Sarah E. Hunt, P. Rodriguez-Tomé, Anindya Dehejia, D. R. Cox, Mihael H. Polymeropoulos, Carol Soderlund, Xufeng S. Wu, L. Green, S. Keil, Tara C. Matise, T. Dibling, Sidney W. Fox, and Adam Butler

Subjects
Expressed Sequence Tags, Genetic Markers, Genetics, Internet, Expressed sequence tag, Multidisciplinary, Positional cloning, Gene map, Genome, Human, Gene Expression, Computational biology, Biology, Physical Chromosome Mapping, ENCODE, Rats, Sequence-tagged site, Gene mapping, Human Genome Project, Animals, Chromosomes, Human, Humans, Radiation hybrid mapping, Human genome, Sequence Tagged Sites
Abstract

A map of 30,181 human gene–based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The new gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site ( www.ncbi.nlm.nih.gov/genemap ) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross-referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.

Published
1998
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