The SEARCH, TODAY, and HEALTHY studies, and NASN's SCOPE intervention, illustrate that collaboration between schools, school nurses, clinicians, students, and families can help treat and prevent diabetes and obesity in youth. Findings will help identify the prevalence of diabetes in young people, the best ways to treat youth with new-onset type 2 diabetes, and healthful practices that can reduce risk factors for cardiovascular disease. Findings about diabetes prevention in the school setting can guide school nurses and school leadership to incorporate effective changes into food and physical activity offerings to students. Finally, school nurses can communicate with primary care providers and provide culturally sensitive letters to parents and guardians regarding the BMI results for the child.