Search

Proceeding from TeCl and 1-octene a regioselective method was developed of the synthesis of trichloro(2-chlorooctyl)tellane. At adding methanol to this compound chlorine was easily replaced at room temperature by a methoxy group affording trichloro(2-methoxyoctyl)tellane. The reaction of TeBr with 1-octene in methanol resulted in tribromo(2-methoxyoctyl)tellane. A reduction of trichloro- and tribromo(2-methoxyoctyl)tellanes occurs the most selectively in the system NaBH4-water-THF giving 1,2-bis(2-methoxyoctyl)ditellane. The reactions are characterized by a high selectivity and quantitative yields of the products. [ABSTRACT FROM AUTHOR]

Ethyl 7-aryl-6,8-dioxo-2-oxa-3,7-diazabicyclo[3.3.0]oct-3-ene-4-carboxylates and ethyl 7-aryl-6,8-dioxo-1-oxa-2,7-diazaspiro[4.4]non-2-ene-3-carboxylates were selectively reduced with sodium tetrahydridoborate at the carbonyl group in the β-position with respect to the oxygen atom in the isoxazole ring. [ABSTRACT FROM AUTHOR]

The reactions of 2-amino-3-nitropyridine and 2-amino-5-nitropyridine with hydrazine hydrate resulted in elimination of the amino group and reduction of the nitro group with formation of 3-aminopyridine. A probable reaction mechanism involves addition of hydrazine hydrate at the N-C2 bond, followed by elimination of ammonia and reduction of the nitro group to amino. 2-Amino-4-methyl-3-nitropyridine and 2-amino-5-methyl-3-nitropyridine reacted with hydrazine hydrate in a similar way. [ABSTRACT FROM AUTHOR]

Reduction of alkyl-2-amino-5,6-dialkyl-3-cyanopyridine-4-carboxylates with sodium borohydride in protic solvents gave rise to 4-amino-3-imino-6,7-dialkyl-1,3-dihydrofuro[3,4- c]pyridines that at hydrolysis in acid medium afforded the corresponding lactones. [ABSTRACT FROM AUTHOR]

The article presents a study regarding the chemical reduction of N-(2-nitro-4-R-phenyl) pyridinium salts and their reaction with N-(2-amino-4-R-phenyl)pyridinium chlorides. The study identified the two simultaneous chemical transformations that complicate the analysis of this reaction, which include the reduction and the intramolecular cyclization. The article also presents a table that shows the results of the study.

In this article the author argues that the reduction of expoxynorbornanes is accompanied by heterocyclization processes. Here the authors present an examination of the reduction of N-(m-tolyl)-exo-2,3- epoxybicyclolheptane-endo-5,endo-6-dicarhoximide(III) under analogous conditions. When the reduction of III was carried out, the researchers isolated by column chromatography on silica gel diol V and compound VI in 7.5 and 38.3 or 9.2 and 57.2% yield, respectively. The structure of VI was proved by the X-ray diffraction data.

The article offers information on reductive dechlorination of cyclopentadiene-dichloroketene adduct with zinc in acetic acid, which leads to the formation of ketone. Ketones from the chemical process are used in the synthesis of prostaglandins and other cyclopentanoids. It states that the reaction results into loss of water-soluble lactones during their isolation from acidic medium.

The article studies the use of sulphur or its mixture with morpholine as a safe, accessible and selective reducing agent for the transformation of benzofuroxans into benzofurazans. According to the authors, the addition of morpholine to the reaction mixture enhances the reactivity of sulphur. They add the reaction time in the reduction of benzofuroxan is decreased and the yield of benzofurazan increases. They also describe the general procedure for the reduction of benzofuroxans with sulphur.

Treatment of 3,4-bis(formylamino)pyridine with a mixture of concentrated nitric and sulfuric acids unexpectedly afforded 4-nitro-1,2,3-triazolo[4,5-c]pyridine 2-oxide. Reduction of the latter with iron in acetic acid gave previously known 4-amino-1,2,3-triazolo[4,5-c]pyridine. [ABSTRACT FROM AUTHOR]