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Your search keyword '"A. V. Gopin"' showing total 2 results
Start Over Author "A. V. Gopin" Journal russian journal of general chemistry
2 results on '"A. V. Gopin"'

1. Combined method of ultrasound therapy of oncological diseases

Author

L. V. Demidov, D. V. Filonenko, B. Yu. Bokhyan, A. V. Gopin, O. L. Kaliya, B. Ya. Kogan, Viktor Evgenievich Bozhevolnov, I. N. Mikhailova, A. L. Nikolaev, E. V. Khorosheva, G. K. Gerasimova, H.M. Treshalina, S. E. Mazina, I. V. Melikhov, and N. V. Andronova

Subjects
medicine.medical_specialty, business.industry, Chemistry, Ultrasound, Scientific institution, Cancer, General Chemistry, medicine.disease, Clinical trial, Joint research, medicine, Medical physics, business, Combined method, Federal state
Abstract

The experience of the joint research by the Department of Chemistry, Lomonosov Moscow State University, and the Federal State Budgetary Scientific Institution “N.N. Blokhin Russian Cancer Research Center” (FSBSI “N.N. Blokhin RCRC”), on the application of medium-intensity ultrasound in combination with chemotherapy and sonosensitizers in the treatment of cancer diseases was summarized. A cycle of preclinical trials showed that the method allows enhancing the damaging effect of ultrasound on the tumor, while no metastasis-promoting and toxic effects are exerted. The combined method is being currently tested in clinical trials.

Published
2015

2. Thermoresponsive hydrogels with ultrasound-controlled properties

Author

D. S. Chicherin, A. L. Nikolaev, A. V. Gopin, Viktor Evgenievich Bozhevolnov, and V. L. Zelenko

Subjects
Kinetic model, business.industry, Chemistry, Hydrogel matrix, Phase (matter), Ultrasound, Self-healing hydrogels, Drug release, Ultrasound exposure, Nanotechnology, General Chemistry, business
Abstract

Possibility of creation of materials with transport properties operated by ultrasound on the basis of thermosensitive hydrogels modified by a solid phase of inorganic compounds is shown. The kinetic model of drug release from the hydrogel matrix, which allows to optimize the parameters of ultrasound exposure is proposed. Various options of devices with operated ultrasound an outlet of medicinal substance are offered.

Published
2014

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