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The decomposition of aluminum hydride complexes with trimethylamine and N-heterocyclic carbene—1,3-bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene was studied by a static tensimetric method with a membrane null-manometer. The AlH3·NMe3 complex passes into vapor in the form of monomeric molecules and in unsaturated vapor slowly decomposes at 70‒80°С into solid aluminum, gaseous trimethylamine, and hydrogen. The decomposition is accompanied by an induction period, the duration of which decreases as temperature increases. The AlH3 complex with carbene slowly decomposes at 170‒200°С with a rate practically independent of temperature. [ABSTRACT FROM AUTHOR]

Removal of the ethoxycarbonyl group in ethyl cyano-(2,2-dimethyl-4-propyltetrahydro-2H-pyran-4 -yl)acetate afforded the corresponding (2,2-dimethyl-4-propyltetrahydro-2H-pyran-4-yl)acetonitrile. The reduction of the latter with lithium aluminum hydride furnished 2-(2,2-dimethyl-4-propyltetrahydro-2H-pyran- 4-yl)ethanamine, which reacted with furfural and a heterocyclic ketone followed by reduction to form the secondary amines and some amides. Hydrolysis of the above nitrile resulted in the corresponding acid, which was converted in a series of amides. [ABSTRACT FROM AUTHOR]

Reduction of unsaturated adamantyl-containing nitriles with lithium aluminum hydride in 2-methyltetrahydrofuran was examined. It was found that under the synthesis conditions a simultaneous reduction of the double bond and the nitrile group successfully occurred. The presence of bulky substituents in the α-position to the adamantyl moiety of nitriles led to a significant increase in the synthesis duration. A satisfactory yield of the target compounds was achieved only by increasing the temperature and using a two-fold excess of lithium aluminum hydride. [ABSTRACT FROM AUTHOR]

Hydrogenation of terminal β-acetylene alcohols with lithium aluminum hydride in THF has afforded homoallylic alcohols. Decomposition of the intermediate organoaluminum complex with deuterated water, iodine, or pyridinium dibromide has evidenced about the non-regioselective hydride attack at the triple bond. [ABSTRACT FROM AUTHOR]

Results of investigation of selective hydrogenation of unsaturated carbon-carbon bonds with hydrazine hydrate or complex metal hydrides in the presence of metal nanoparticles are reported. Conditions of exhaustive and partial hydrogenation of some derivatives of norbornene, styrene, and unsaturated carboxylic acids are developed. [ABSTRACT FROM AUTHOR]

Aminomethylation of 1-(4-butoxyphenyl)-2-phenylethanone with paraformaldehyde and substituted piperazines in ethanol medium results in 1-(4-butoxyphenyl)-3-(4-R-piperazin-1-yl)-2-phenylpropan-1-ones. The latter react with cyclohexylmagnesium halide to give 1-(4-butoxyphenyl)-1-cyclohexyl-3-(4-arylpiperazin-1-yl)-2-phenylpropan-1-ols. Reduction of the prepared β-aminoketones with lithium aluminum hydride in absolute diethyl ether leads to the secondary aminopropanols. The prepared compounds could be converted into the corresponding dihydrochlorides. [ABSTRACT FROM AUTHOR]

New 1-organyl-2-azasilatran-3-ones have been synthesized via the reaction of trifunctional silanes RSiX (R = Et, Pr, Ph, CH=CH, or ClCH; X = Cl or MeN) with N,N-bis(2-hydroxyethyl)glycinamides (HOCHCH)NCHC(O)NHR (R = H or Me) and their N′,O-trimethylsilyl derivatives. The obtained products can be hydrolyzed to give the corresponding organylsilanetriols. Lithiation of 1-methyl- and 1-phenyl-2-azasilatran-3-ones with n-butyllithium or their reduction with lithium aluminum hydride leads to the products of splitting of the atrane backbone RSiBu and RSiH (R = Me or Ph), respectively. [ABSTRACT FROM AUTHOR]

The interaction of Co(acac) with LiAlH4 or LiAlH( t-BuO) was studied using NMR, UV, IR, ESR spectroscopy, electron microscopy, and volumometry. The basic stages of formation of cobalt catalysts for hydrogenation were suggested. The formation of the nanoparticles that are active in the hydrogenation process is shown to occur at a ratio of reagents 5 ≤ Red/Co ≤ 12. The nanoparticles are stabilized by an excess of LiAlH or LiAlH( t-BuO), as well as by the products of their catalytic decomposition under the action of cobalt in the reduced state. At the ratio LiAlH / Co> 12 to obtain the particles active in catalysis their activation by a proton-donor compound is required. [ABSTRACT FROM AUTHOR]

A letter to the editor is presented which investigates the use of lithium aluminum hydride to reduce ethylene glycol monopropargyl ether.