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Acute pancreatitis is an acute inflammatory process of the pancreatic acinar cells. In severe cases of acute pancreatitis development can lead to multiple organ dysfunction. International studies in recent decades have highlighted numerous prognostic factors in severe acute pancreatitis: clinical, biological, intraopera-tive and pathological. Our research aims to identify the factors of prognosis in severe acute pancreatitis. The study was prospective and included a sample of 238 patients diagnosed with acute pancreatitis and its complications. Of all patients, 43.28% had severe acute pancreatitis, and 58.83% were male. Age over 55 years was found in 52.43% of patients with severe form and only 33.33% of patients with mild form. Female patients with obesity and aged between 60 and 80 years more frequently develop acute pancreatitis. Mortality among obese patients with the severe form is four times higher than in obese patients with mild form. Although female patients appear more frequently develop complications, total number of deaths occurring in obese patients is higher in males compared to the females. Conclusion. Age and obesity are factors useful for more precise prediction of severity of acute pancreatitis. [ABSTRACT FROM AUTHOR]

Background. The aim of the study was to assess the prevalence of uncontrolled hypertension and its characteristics in comparison with controlled hypertension. Material and method. 3,145 hypertensive patients from 19 family medicine practices of Timiş County were evaluated from 2010 to 2014 clinically and by laboratory. Results. After 12 months of monitoring, 1008 patients (32.05%) had controlled hypertension and 2137 (67.95%) had office BP > 140/90 mmHg, being considered uncontrolled. ABPM was performed in 690 patients with uncontrolled hypertension and it allowed to diagnose a “white-coat“ effect in 34.18% of them, as they had normal blood pressure values recorded with ABPM. Abnormal values were found in 520 (65.82%), of which 360 (69.23%) were uncontrolled by treatment, 85 (16.35%) were untreated, 42 (8.08%) had resistant hypertension and 33 (6.34%) secondary hypertension. The most common causes of uncontrolled hypertension were: poor adherence to treatment, inadequate doses and combinations, excessive salt consumption, obesity, metabolic syndrome, secondary and resistant hypertension. Compared with controlled hypertension, uncontrolled hypertensive patients were more often older, presented more severe and long hypertension evolution, organ damage and cardiovascular complications. [ABSTRACT FROM AUTHOR]