1. Prevalence of other connective tissue diseases in idiopathic inflammatory myopathies
- Author
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Vidya Limaye, Adam Maundrell, and Susanna Proudman
- Subjects
medicine.medical_specialty ,Databases, Factual ,Biopsy ,Immunology ,Connective tissue ,Gastroenterology ,Polymyositis ,Mixed connective tissue disease ,Rheumatology ,Internal medicine ,South Australia ,Prevalence ,Humans ,Immunology and Allergy ,Medicine ,Connective Tissue Diseases ,Myositis ,Autoantibodies ,Retrospective Studies ,Scleroderma, Systemic ,Muscle biopsy ,medicine.diagnostic_test ,business.industry ,medicine.disease ,Connective tissue disease ,medicine.anatomical_structure ,Rheumatoid arthritis ,business ,Biomarkers - Abstract
We sought to determine the prevalence of additional connective tissue diseases (CTDs) in patients with idiopathic inflammatory myopathies (IIM), and to study the muscle biopsy patterns in various clinico-serologic subsets of myositis. We undertook a retrospective cohort study of 648 patients with a histological diagnosis of IIM. The following was determined from the South Australian Myositis Database: presence of associated CTDs, histological details and presence of myositis-specific (MSA) or myositis-associated (MAA) antibodies. Among patients with IIM, a significantly greater proportion had systemic sclerosis 32/648 (4.9%) than mixed connective tissue disease (12/648, p = 0.003), primary Sjogren’s syndrome (12/648, p = 0.003), systemic lupus erythematosus (10/648, p
- Published
- 2019
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