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1. From exposure to allergen to onset of an allergic disease

Author

Vervloet, D.

Subjects
*ALLERGENS, *ASTHMA, *ALLERGIES
Abstract

In this paper, special consideration will be given to the following points:

  • Is there a causal relationship between exposure to aeroallergens and allergic sensitization?
  • Is there a causal relationship between sensitization and occurrence of allergic disease?
  • Is there a causal relationship between exposure to allergen and occurrence of allergic disease?
  • Are symptom severity and the morbidity of allergic diseases related to the level of exposure to environmental allergen?
    • A review of the literature indicates that, in most circumstances, there is a significant relationship between the level of exposure and the degree of sensitization to a given allergen. However, recent studies indicate that early contact with dogs and cats may in fact prevent sensitization in some children who are at risk. On the other hand, there is a relationship between sensitization and the occurrence of allergic disease, but in general there is no causal relationship between the degree of exposure to allergen and the occurrence of disease. In contrast, the severity of symptoms and the morbidity of allergic diseases are related to the level of exposure to environmental allergens [Copyright &y& Elsevier]

    Published
    2003