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Abstract: Aim. – To evaluate the publication output associated with research on asthma in children. Methods. – The data encompassed the period from 1991 to 2002 and were extracted from the Science Citation Index online version. Selected documents included ‘asthmatic children’ and ‘asthma children’ as a part of its title, abstract, or keyword from. Parameters analyzed included language, type of document, page count, publication output, country of publication, authorship, publication pattern, and the most frequently cited paper. Results. – The yearly publications have increased from 1991 to 2002. The seven industrialized countries have high productivity in this research field. English was the dominant language, and four or five authors were the moot common number of co-author. The US was the world leader and dominated most of the publications, followed by the UK. Conclusions. – The most important functions of scientific publications are to communicate and exchange research findings and results. The results of the study not only offer a comprehensive picture of asthma in children by bibliometric research, but also demonstrate the performance of research workers, institutions, and even countries. [Copyright &y& Elsevier]

Evidence from many animal and human studies suggests that hemopoietic processes play an active role in allergy. This systemic aspect of allergic inflammation, involving the bone marrow, may explain associations noted among various atopic diseases and their manifestations, clinically and epidemiologically. Understanding the nature of this systemic process in allergy may lead to new, possibly more effective therapeutic approaches in the future. In this paper, we review specific hemopoietic mechanisms that are involved in the development of upper and lower airway inflammation, focusing on allergic rhinitis, asthma and nasal polyposis in human and animal studies. We describe the in vivo and in vitro effects of several anti-allergic modalities on these processes, concluding that the targeting of hemopoietic progenitors may be an essential requirement of effective therapy for allergic disease. [Copyright &y& Elsevier]