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Start Over Author "Jaisson, S." Journal revue des maladies respiratoires
3 results on '"Jaisson, S."'

3. [Involvement of inorganic phosphate starvation in Pseudomonas aeruginosa bacterial virulence].

Author

Jahdauti L, Muggeo A, Paturel V, Jaisson S, Luczka E, Coraux C, and Guillard T

Subjects
Humans, Bacterial Proteins metabolism, Virulence, Bacteria, Phosphates metabolism, Pseudomonas aeruginosa
Abstract

Pseudomonas aeruginosa is a bacterium causing a wide spectrum of nosocomial and opportunistic respiratory infections. As an element essential for bacterial metabolism , phosphorus is incorporated as an inorganic phosphate and regulated by a two-component PhoB-PhoR system. Recently, it has been shown that as a result of overexpression of virulence factors, including the PhoB transcription factor, P. aeruginosa exhibited increased virulence in phosphate-deficient conditions. Exploration of the relationship between phosphate homeostasis and P. aeruginosa virulence could effectively contribute to the development of new, simple and innovative therapeutic strategies., (Copyright © 2023 SPLF. Published by Elsevier Masson SAS. All rights reserved.)

Published
2023
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