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Start Over Author "J. Franco" Journal revista clinica espanola
15 results on '"J. Franco"'

1. Hemoconcentración como predictor de supervivencia al año de ingreso por insuficiencia cardiaca aguda en el registro RICA

Author

J. Grau Amorós, F. Formiga, O. Aramburu Bodas, A. Armengou Arxe, A. Conde Martel, M.A. Quesada Simón, R. Oropesa Juanes, J.A. Satué Bartolomé, M.F. Dávila Ramos, M. Montero Pérez-Barquero, L. Anarte, O. Aramburu, J.C. Arévalo-Lorido, A. Armengou, A. Brase, S. Carrascosa, M. Carrera, J. Casado, J.M. Cerqueiro, A. Conde, M.F. Dávila, J. Díez-Manglano, F. Epelde, J. Franco, J. Gallego, D. García-Escrivá, A. González-Franco, J. Grau, M.E. Guisado, A. Herrero, P. Llacer, G. López-Castellanos, L. Manzano, A. Martínez-Zapico, M. Montero-Pérez-Barquero, A. Muela, R. Oropesa, C. Pérez-Bocanegra, J.I. Pérez-Calvo, J. Pérez-Silvestre, M.A. Quesada, R. Quirós, E.E. Rodríguez-Ávila, F. Ruiz-Laiglesia, R. Ruiz-Ortega, P. Salamanca, M. Sánchez-Marteles, J.A. Satué, A. Serrado, I. Suárez, and J.C. Trullàs

Subjects
03 medical and health sciences, 0302 clinical medicine, business.industry, Medicine, 030212 general & internal medicine, General Medicine, business, Humanities
Abstract

Resumen Objetivo Diferentes estudios senalan que la consecucion de una mayor hemoconcentracion en pacientes ingresados por insuficiencia cardiaca (IC) aguda mejora el pronostico a lo largo del ano siguiente al episodio indice. El objetivo de este estudio es evaluar si el grado de hemoconcentracion a los 3 meses tras el ingreso por IC tambien tiene valor pronostico de reingreso y/o mortalidad en los 12 meses siguientes al ingreso. Pacientes y metodo Cohorte prospectiva multicentrica de 1.659 pacientes con IC. El grupo hemoconcentracion (305 pacientes) se situo en el cuartil superior de la muestra distribuida en funcion del aumento de la hemoglobina en el mes 3 tras el alta con respecto a la hemoglobina en el ingreso por IC. Resultados Seguimiento medio hasta el primer evento fue de 294 dias, fallecieron 487 pacientes y reingresaron 1.125. El grupo hemoconcentracion mostro un riesgo menor de mortalidad o de reingreso por cualquier causa (RR = 0,75; IC 95%: 0,51-1,09 y RR = 0,86; IC 95%: 0,70-1,05), si bien la significacion estadistica se perdio tras el analisis multivariado. Sin embargo, esta significacion se mantuvo para otros factores con reconocido efecto negativo sobre el pronostico en pacientes con IC, como son la edad y la clase funcional. Conclusiones El grado de hemoconcentracion a los 3 meses tras el ingreso por IC no tiene valor pronostico de reingreso o muerte en el ano siguiente.

Published
2019
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5. Tomografía computarizada de alta resolución en tuberculosis pulmonar con baciloscopia de esputo negativa

Author

J. Franco Serrano, I. Inchaurraga Álvarez, J. Marín Pardo, E. González Constán, R. Blanquer Olivas, and M.L. Domingo Montañana

Subjects
Gynecology, medicine.medical_specialty, business.industry, medicine, General Medicine, business
Abstract

Marco de referencia La tuberculosis pulmonar con baciloscopia de esputo negativa plantea dificultades diagnosticas cuando no se dispone de medios liquidos de cultivo debido al lento crecimiento del Mycobacterium tuberculosis en los medios tradicionales de cultivo y a la necesidad de utilizar exploraciones invasivas. Objetivo Evaluar los hallazgos de la tomografia computarizada de alta resolucion (HRCT) en pacientes con tuberculosis pulmonar y baciloscopia de esputo negativa. Metodo Se estudiaron prospectivamente 28 pacientes (12 con tuberculosis activa y 16 inactiva) mediante HRCT, valorando los siguientes hallazgos: nodulos centrolobulillares, estructuras lineales ramificadas multiples, macronodulos, cavitacion, consolidacion, engrosamiento de septos interlobulillares, vidrio esmerilado, bronquiectasias, enfisema, distorsion broncovascular, cambios fibroticos, adenopatias mediastinicas calcificadas, calcificacion parenquimatosa, engrosamiento pleural y derrame pleural. Resultados Los hallazgos que se asociaron significativamente a enfermedad activa fueron: consolidacion (67%), macronodulos (67%) y nodulos centrolobulillares (67%). La presencia de nodulos centrolobulillares y/o consolidacion tuvo una sensibilidad del 83% y especificidad del 87%. Los hallazgos que se asociaron significativamente a enfermedad inactiva fueron bronquiectasias (87%) y distorsion broncovascular (62%). Conclusion Nuestros resultados apoyan el valor de la HRCT en pacientes con tuberculosis pulmonar y baciloscopia de esputo negativa, ya que el hallazgo de nodulos centrolobulillares y/o consolidacion tiene una buena sensibilidad y especificidad para diagnosticar enfermedad pulmonar activa.

Published
2003
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6. [High resolution computerized tomography in pulmonary tuberculosis with negative sputum bacilloscopy]

Author

E, González Constán, J, Franco Serrano, M L, Domingo Montañana, I, Inchaurraga Alvarez, R, Blanquer Olivas, and J, Marín Pardo

Subjects
Male, Sputum, Humans, Female, Prospective Studies, Middle Aged, Tomography, X-Ray Computed, False Negative Reactions, Tuberculosis, Pulmonary
Abstract

Pulmonary tuberculosis with negative sputum bacilloscopy involves diagnostic difficulties when there are not available liquid culture media due to the slow growth of Mycobacterium tuberculosis in the traditional culture media, and also due to the need for carrying out invasive examinations.Evaluate the high resolution computerized tomography findings (HRCT) in patients with pulmonary tuberculosis and negative bacilloscopy of sputum.Prospectively 28 patients (12 with active tuberculosis and 16 with inactive tuberculosis) were evaluated through HRCT, assessing the following findings: centrolobular nodules, multiple branched linear structures, macronodules, cavitation, consolidation, enlargement of interlobular septums, ground-glass change, bronchiectases, emphysema, broncovascular distortion, fibrotic changes, calcified mediastinal adenopathies, parenchymous calcification, pleural enlargement, and pleural effusion.The findings that were associated significantly to the active disease were: consolidation (67%), macronodules (67%) and centrolobular nodules (67%). The presence of centrolobular nodules and/or consolidation had a sensitivity of 83% and a specificity of 87%. The findings significantly associated to inactive disease were bronchiectases (87%) and broncovascular distortion (62%).Our results support the value of HRCT in patients with pulmonary tuberculosis and negative sputum bacilloscopy, since the finding of centrolobular nodules and/or consolidation has good sensitivity and specificity for the diagnosis of active pulmonary disease.

Published
2003

8. The short-term prognostic value of C-reactive protein in elderly patients with acute heart failure.

Author

Chivite D, Franco J, Formiga F, Salamanca-Bautista P, Manzano L, Conde-Martel A, Arévalo-Lorido JC, Suárez-Pedreira I, Casado-Cerrada J, and Montero-Pérez-Barquero M

Abstract

Introduction and Objectives: Plasma c-reactive protein (crp) has been tested as a prognostic marker in acute heart failure (ahf). Whether its measurement really provides significant prognostic information when applied to elderly patients with ahf episodes remains unclear., Methods: We measured the plasma crp values of patients admitted because of any type of ahf to internal medicine services. We evaluated the association of these values with the patients' baseline clinical characteristics and their 3-month posdischarge all-cause mortality or readmission rates. For comparison purposes, we divided the sample in tertiles of low, medium and high crp values (<2,24mg/l, 2,25-11,8mg/l and>11,8mg/l)., Results: We included 1443 patients with a median age of 80 years (interquartile range 73-85); 680 (47%) were men, with a moderate comorbid burden. 60.1% had preserved left ventricular ejection fraction (> 50%). Multivariate analysis confirmed an independent association between higher crp values and the presence of respiratory infection, lower systolic blood pressure and deteriorated renal function upon admission. Three months after the index admission, a total of 142 patients (9.8%) had died, and 268 (18.6%) had either been readmitted or died. admission crp values did not correlate with 3-month all-cause mortality (P=0.79), 3-month all-cause readmission (P=0.96) or the combination of both events (P=0.96). However, higher crp values were associated with a longer length of stay (P<0.001)., Conclusion: Our study does not confirm an association between admission plasma crp values in elderly ahf patients and subsequent higher 3-month mortality or readmission risks., (Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.)

Published
2019
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10. [High resolution computerized tomography in pulmonary tuberculosis with negative sputum bacilloscopy].

Author

González Constán E, Franco Serrano J, Domingo Montañana ML, Inchaurraga Alvarez I, Blanquer Olivas R, and Marín Pardo J

Subjects
False Negative Reactions, Female, Humans, Male, Middle Aged, Prospective Studies, Sputum microbiology, Tuberculosis, Pulmonary microbiology, Tomography, X-Ray Computed, Tuberculosis, Pulmonary diagnostic imaging
Abstract

Context: Pulmonary tuberculosis with negative sputum bacilloscopy involves diagnostic difficulties when there are not available liquid culture media due to the slow growth of Mycobacterium tuberculosis in the traditional culture media, and also due to the need for carrying out invasive examinations., Objective: Evaluate the high resolution computerized tomography findings (HRCT) in patients with pulmonary tuberculosis and negative bacilloscopy of sputum., Method: Prospectively 28 patients (12 with active tuberculosis and 16 with inactive tuberculosis) were evaluated through HRCT, assessing the following findings: centrolobular nodules, multiple branched linear structures, macronodules, cavitation, consolidation, enlargement of interlobular septums, ground-glass change, bronchiectases, emphysema, broncovascular distortion, fibrotic changes, calcified mediastinal adenopathies, parenchymous calcification, pleural enlargement, and pleural effusion., Results: The findings that were associated significantly to the active disease were: consolidation (67%), macronodules (67%) and centrolobular nodules (67%). The presence of centrolobular nodules and/or consolidation had a sensitivity of 83% and a specificity of 87%. The findings significantly associated to inactive disease were bronchiectases (87%) and broncovascular distortion (62%)., Conclusion: Our results support the value of HRCT in patients with pulmonary tuberculosis and negative sputum bacilloscopy, since the finding of centrolobular nodules and/or consolidation has good sensitivity and specificity for the diagnosis of active pulmonary disease.

Published
2003
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11. [Hereditary hemorrhagic telangiectasia at an internal medicine service: study of 12 patients].

Author

Cabañes Argudo M, Villar Grimalt A, Puche Azorín P, Franco Serrano J, and Brotons Brotons B

Subjects
Adolescent, Adult, Aged, Female, Hospital Departments, Humans, Internal Medicine, Male, Middle Aged, Pedigree, Spain, Telangiectasia, Hereditary Hemorrhagic diagnosis, Telangiectasia, Hereditary Hemorrhagic genetics
Abstract

Hereditary hemorrhagic telangiectasia (HHT) is a hereditary dominant autosoma clinical entity characterized by repeated hemorrhages (being epistaxis the more frequent) and telangiectasia in skin, mucosa and internal organs. Incidence in Europe is 1,2 per 100,000 pop. We discuss the experience of an Internal Medicine Department (Arnau de Vilanova Hospital), during 10 years, in which 12 patients were diagnosed. With the aim to provide more information about this rare disease. There was no predominant sex and the age of onset was very variable. All patients referred at admission past history of hemorrhages (either the patient him/herself or some relative), or were suffering it at admission. Except one patient, all of them showed telangiectasias in skin and mucosa. In five of them telangiectaias were found in upper gastrointestinal tract, in two there were localized on the tracheobronchial tree and one patient had teleangiectasia in liver. Three patients were diagnosed of pulmonary arteriovenous fistula (PAVF). The clinical, diagnostic and therapeutic aspects of this disease are reviewed.

Published
1992

13. [Hypertrophic osteoarthropathy, gynecomastia and vascular spiders in relation to increased estrogen production as the initial manifestation of a lung epidermoid carcinoma].

Author

Suárez Ortega S, Carvajal Ledezma J, Franco Cebrián J, and Lorente Cruz A

Subjects
Aged, Carcinoma, Squamous Cell complications, Diagnosis, Differential, Gynecomastia etiology, Humans, Lung Neoplasms complications, Male, Osteoarthropathy, Secondary Hypertrophic etiology, Paraneoplastic Syndromes etiology, Telangiectasis etiology, Carcinoma, Squamous Cell diagnosis, Estrogens blood, Gynecomastia diagnosis, Lung Neoplasms diagnosis, Osteoarthropathy, Secondary Hypertrophic diagnosis, Paraneoplastic Syndromes diagnosis, Telangiectasis diagnosis
Published
1990

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