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The article explores Brazil's efforts to implement a One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. Brazil, as a populous and biodiverse country with a significant role in food production, has prioritized One Health and taken steps to prevent and control diseases. The COVID-19 pandemic has highlighted the importance of global coordination and governance in implementing One Health. The Ministry of Health in Brazil has undertaken various initiatives, including promoting a National Day of One Health and updating surveillance actions for zoonoses and vector-borne diseases. Brazil is also supporting global One Health initiatives and has formed an interinstitutional group to develop a National Action Plan for One Health. Collaboration and interdisciplinary work are emphasized as crucial in addressing complex health challenges. [Extracted from the article]