1. Balo's concentric sclerosis: an update and comprehensive literature review
- Author
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Mehdi Abbasi, Hossein Pakdaman, Ali Amini Harandi, Akram Esfandani, and Mohammad Ali Sahraian
- Subjects
medicine.medical_specialty ,Neurology ,Multiple Sclerosis ,medicine.medical_treatment ,Spontaneous remission ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,Severe disability ,Myelin Sheath ,medicine.diagnostic_test ,business.industry ,General Neuroscience ,Multiple sclerosis ,Brain ,Immunosuppression ,Magnetic resonance imaging ,Diffuse Cerebral Sclerosis of Schilder ,medicine.disease ,Magnetic Resonance Imaging ,Pathophysiology ,Concentric sclerosis ,Radiology ,business ,030217 neurology & neurosurgery ,Demyelinating Diseases - Abstract
Balo’s concentric sclerosis (BCS) is considered a variant of multiple sclerosis characterized by concentric lamella of alternating demyelinated and partially myelinated tissues. It is a rare and a relatively acute condition. Attacks may proceed rapidly over weeks or months, typically without remission, like Marburg’s variant, resulting in death or severe disability. However, the majority of cases have a more benign, self-limiting course with spontaneous remission. Magnetic resonance imaging is a primary imaging modality in the diagnosis of BCS. Treatment with intense immunosuppression may be indicated in patients with more aggressive form. New reports reveal more evidence regarding the pathophysiology and treatment strategies.
- Published
- 2017