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6 results on '"Lutz Freitag"'

1. Bronchoscopic Lung Volume Reduction with Endobronchial Valves in Low-FEV1 Patients

Author

Paul Zarogoulidis, Filiz Oezkan, Clemens Aigner, Rüdiger Karpf-Wissel, Stefan Welter, Stephan Eisenmann, Lutz Freitag, Kaid Darwiche, and Wolfgang Hohenforst-Schmidt

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, medicine.diagnostic_test, business.industry, respiratory system, Lung volume reduction surgery, medicine.disease, respiratory tract diseases, Surgery, Pulmonary function testing, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Pneumothorax, Quality of life, Bronchoscopy, Severity of illness, medicine, Lung emphysema, 030212 general & internal medicine, Radiology, Complication, business
Abstract

Background: Bronchoscopic lung volume reduction (BLVR) with valves has been shown to improve lung function, exercise capacity, and quality of life in patients with emphysema, but only few patients with forced expiratory volume in 1 s (FEV1) ≤20% predicted have been included in former studies. Although the procedure can be performed safely, pneumothorax is a frequent complication, which can be critical for these very severely diseased patients. Objectives: The aim of the study was to assess the safety of BLVR in patients with a very advanced stage of emphysema, as indicated by FEV1 ≤20% predicted. Patients and Methods: Patients in whom BLVR was performed between January 2013 and August 2015 were included in this analysis if their baseline predicted FEV1 was ≤20%. BLVR, performed only if collateral ventilation was absent, achieved complete occlusion of the target lobe. All patients were closely monitored and were not discharged before the fourth day after BLVR. Results: Twenty patients with FEV1 ≤20% predicted were included in the analysis. Lung volume reduction was achieved in 65% of the cases. Pneumothorax occurred in 4 cases (20%). No patient died. Lung function and exercise tolerance improved after 1 and 3 months, respectively. Conclusions: BLVR with valves can be safely performed in patients with FEV1 ≤20% predicted when close postprocedural monitoring is provided. Improvement in lung function and exercise capacity can be achieved.

Published
2016

2. Biodegradable Airway Stents - Bench to Bedside: A Comprehensive Review

Author

Sophie Laroumagne, Ali I. Musani, Philippe Astoul, Lutz Freitag, Kaid Darwiche, and Hervé Dutau

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Bronchoscopic procedure, business.industry, medicine.medical_treatment, Medizin, Stent, equipment and supplies, Bench to bedside, Surgery, Airway Obstruction, surgical procedures, operative, Stent removal, Absorbable Implants, Animals, Humans, Medicine, Stents, cardiovascular diseases, Tracheal Stenosis, business, Airway
Abstract

Airway stents are indicated to treat symptomatic narrowing or to close fistulas of the central airways. They are generally divided into two types: the silicone stents and the metallic stents. Unlike in malignancies, removability is a major objective of temporary stenting in benign conditions, which poses the challenge of a new rigid bronchoscopic procedure under general anesthesia and stent removal with all its attendant risks and costs. The concept of a biodegradable (BD) stent that could maintain the patency of an airway for a predetermined duration of time is very appealing. These BD stents would gradually degrade and eventually vanish from the airway once they are no longer needed. Such stents are currently an area of intense research. Another very promising concept of drug delivery with such stents is also a very exciting area of current research. The aim of this comprehensive review is to discuss all pertinent available literature on the use of BD materials in various clinical applications and to extensively review all animal and humans trials involving BD airway stents.

Published
2015

3. Contents Vol. 87, 2014

Author

Masakazu Yoshioka, Hugo Goulart de Oliveira, Manuel Schlageter, Philipp Latzin, Marina Saetta, Koji Sakamoto, Sylvia Verbanck, Samuel V. Kemp, Naohiro Watanabe, Osamu Nishiyama, Michael Tamm, Ravi Mahadeva, Manuel G. Cosio, Florian Singer, Salman Siddiqui, Alexandar Tzankov, Hiroyuki Taniguchi, Tsogyal D. Latshang, Werner Druck Medien Ag, Yoshinori Hasegawa, Richard Kraemer, Amisha Singapuri, Liesbeth De Meirleir, Satz Mengensatzproduktion, Malcolm Kohler, Anne Malfroot, Konrad E. Bloch, Kodai Kawamura, Harry J.M. Groen, Lutz Freitag, Eef Vanderhelst, Walter Vincken, Arschang Valipour, Armin Ernst, Daniela Gompelmann, Spasenija Savic, Mark Wiese, Lukas Bubendorf, Steven Corkill, Gerard J. Criner, Yasuhiro Kondoh, Christian M. Lo Cascio, Junya Fukuoka, Kenzo Ono, Dirk-Jan Slebos, Felix J.F. Herth, Bruce Thompson, Kensuke Kataoka, Kazuya Ichikado, Zaid Zoumot, Pallav L. Shah, Riccardo Cazzuffi, Per E. Gustafsson, Kathleen Jahn, Sherif Gonem, Daniel Schuermans, Tomoki Kimura, Ralf Eberhardt, Jos A. Stigt, Thomas Fehr, and Moritaka Suga

Subjects
Pulmonary and Respiratory Medicine, Traditional medicine, business.industry, Medicine, business
Published
2014

4. Gemeinsame Jahresversammlung der Schweizerische Gesellschaft für Pneumologie / Société Suisse de Pneumologie. Schweizerische Gesellschaft für Pädiatrische Pneumologie / Société Suisse de Pneumologie Pédiatrique. Schweizerische Gesellschaft für Thoraxchirurgie / Société Suisse de Chirurgie Thoracique. Schweizerische Vereinigung für Endoskopie Personal / Association Suisse du Personnel en Endoscopie. 8.-9. Mai 2014, Interlaken: Abstracts

Author

Harry J.M. Groen, Christian M. Lo Cascio, Dirk-Jan Slebos, Steven Corkill, Sherif Gonem, Daniel Schuermans, Alexandar Tzankov, Tomoki Kimura, Hiroyuki Taniguchi, Jos A. Stigt, Florian Singer, Satz Mengensatzproduktion, Osamu Nishiyama, Eef Vanderhelst, Yasuhiro Kondoh, Tsogyal D. Latshang, Michael Tamm, Amisha Singapuri, Samuel V. Kemp, Riccardo Cazzuffi, Ravi Mahadeva, Lutz Freitag, Per E. Gustafsson, Kenzo Ono, Marina Saetta, Hugo Goulart de Oliveira, Kazuya Ichikado, Thomas Fehr, Manuel Schlageter, Moritaka Suga, Werner Druck Medien Ag, Walter Vincken, Yoshinori Hasegawa, Zaid Zoumot, Arschang Valipour, Liesbeth De Meirleir, Masakazu Yoshioka, Konrad E. Bloch, Kodai Kawamura, Pallav L. Shah, Philipp Latzin, Bruce Thompson, Felix J.F. Herth, Salman Siddiqui, Manuel G. Cosio, Lukas Bubendorf, Kensuke Kataoka, Malcolm Kohler, Junya Fukuoka, Richard Kraemer, Kathleen Jahn, Ralf Eberhardt, Anne Malfroot, Sylvia Verbanck, Daniela Gompelmann, Mark Wiese, Naohiro Watanabe, Gerard J. Criner, Spasenija Savic, Armin Ernst, and Koji Sakamoto

Subjects
Pulmonary and Respiratory Medicine, Gynecology, medicine.medical_specialty, business.industry, medicine, business
Published
2014

5. Functional Bronchoscopy: Development of a New Bronchoscopic Method for Real-Time Gas Exchange Assessment of Lobes and Lung Segments

Author

Lutz Freitag, Dierik Lenkens, Paul Zarogoulidis, Heiko Hang, Rüdiger Karpf-Wissel, and Kaid Darwiche

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Medizin, Video Recording, Sensitivity and Specificity, Mass Spectrometry, Bronchoscopy, medicine, Humans, Lung, Lung Compliance, Lung function, medicine.diagnostic_test, Pulmonary Gas Exchange, business.industry, respiratory system, Video image, Respiratory support, respiratory tract diseases, Surgery, medicine.anatomical_structure, Breathing, Functional status, Tomography, X-Ray Computed, business, Blood Gas Monitoring, Transcutaneous, Biomedical engineering
Abstract

Background: There are various imaging methods in use designed to provide information on lung functional status, particularly gas exchange within specific lung segments. These complex imaging methods provide indirect information about volume and local lung function. Objectives: The objective of this research was to develop a simpler and more direct method for the functional assessment of gas exchange in lung segments. Method: We have developed a new bronchoscopic method to sample gas concentrations of oxygen and carbon dioxide at the orifices of segmental bronchi in a breathing patient. Endocapnometry and oximetry curves are displayed in real time and superimposed on the endoscopic video images. Results: The gas exchange mapping of a lung could be achieved in Conclusion: This new method enables gas sampling at the lung segment level. The concomitant display of local endocapnometry and endooximetry curves allows for a better identification of target zones for endoscopic emphysema treatments or to improve ventilation strategies for patients on respiratory support.

Published
2014

6. Contents Vol. 88, 2014

Author

Birte Svensson, Cristina Gómez, Gino Soldati, Paul Zarogoulidis, Satz Mengensatzproduktion, Timothy T. Houle, Takahiro Nakajima, Erik H.F.M. van der Heijden, Malcolm Kohler, Borja G. Cosío, Birgit Guldhammer-Skov, Andrea Smargiassi, Giuseppe Maria Corbo, Stylianos E. Orfanos, Laurie A. Hohberger, Norman E. Adair, Christian F. Clarenbach, Zachary S. DePew, Stefanie Zogg, Roberto F. Casal, Rüdiger Karpf-Wissel, Jörg D. Leuppi, James P. Utz, Irtaza Khan, Diana Julie Leeming, Diana Bilton, Francesco Faita, Alessandro Di Marco Berardino, Morten A. Karsdal, Claudia Enz, Sabrina Maier, Eric S. Edell, Federica Genovese, Katharine Hurt, Edward F. Haponik, Cosimo Damiano Inchingolo, Felix Herth, Lutz Freitag, Sara Sher, Susanne Jacobsen, Heiko Hang, Rocco Trisolini, Daniel P Steinfort, Rosanna Nenna, David Miedinger, Giulio Rossi, Salvatore Valente, Rex Yung, Guglielmo M. Trovato, Per Hägglund, Christina Bellinger, Riccardo Inchingolo, Arjun B. Chatterjee, Daniela Catalano, Kaid Darwiche, Selina Dürr, Simon R. Johnson, Andriana I. Papaioannou, Linda Tagliaboschi, Jacob Hull Kristensen, Esther Helen Steveling, Noriane A. Sievi, Jaume Sauleda, Fabien Maldonado, Maurizio Ferretti, Mark Krasnik, Dierik Lenkens, Hanaa Shafiek, Bin Hwangbo, Javier Piérola, Marco Sperandeo, and Werner Druck Medien Ag

Subjects
Pulmonary and Respiratory Medicine, Traditional medicine, business.industry, Medicine, business
Published
2014

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