1. Oocyte donation outcome at TMC Fertility Centre.
- Author
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Lee, C. S. S., Saw, H. L., Chong, W. A., and Kurian, F. J.
- Subjects
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OVUM , *PREGNANCY - Abstract
Introduction: To review the outcome of oocyte donation cases at TMC Fertility Centre for the year 2007. Materials/Methods: This is a retrospective analysis of all oocyte donation treatment cycles in the TMC Fertility Centre for 2007. Oocyte donors were assessed according to ASRM guidelines. Oocyte donation was performed for sub-fertile women with low ovarian reserve. The oocyte donors were either known or anonymous (ratio 1:26). Oocyte recipients, except non-cycling women were down-regulated to synchronize with the donor and subsequently received both oestrogen and progesterone for endometrial development. The oocytes collected then underwent IVF or ICSI. Results: A total of 82 oocyte retrievals were done. Of these, 70 cases progressed to embryo transfer. The mean age of oocyte donors was 25.3 (ranging from 18-45 years old) and for the recipients was 41.1 (ranging from 23-53 years old). A total of 181 embryos were transferred, resulting in 69 pregnancy sacs. The mean number of embryos transferred was 2.6 and the implantation rate was 38.1%. There were 45 clinical pregnancies, giving a clinical pregnancy rate per embryo transfer of 64.3%. The ongoing/delivery rate per embryo transfer was 54.3%. Of the 38 ongoing or delivered pregnancies, 23 are singleton (60.5%), 13 sets are twins (34.2%) and two sets are triplets (5.3%). Conclusions: Oocyte donation offers an effective treatment option for sub-fertile women with low ovarian reserve. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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