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Concomitant use of colchicine and clarithromycin is associated with a potentially life-threatening drug interaction, according to findings of a study published in I Drug Safety i . The potential drug interaction between colchicine and clarithromycin was investigated by searching the US FDA's Adverse Event Reporting System (FAERS) database for case reports in patients eceiving co-administered colchicine and clarithromycin, and searching EMBASE, PubMed and Web of Science databases for articles published between 2015 and 2019 which reported concomitant use of colchicine and clarithromycin. Evidence of Clinically Meaningful Drug-Drug Interaction With Concomitant Use of Colchicine and Clarithromycin. [Extracted from the article]