1. Recommendations for radiation therapy in oligometastatic prostate cancer
- Author
-
Thomas Zilli, Vérane Achard, Alan Dal Pra, Nina Schmidt-Hegemann, Barbara Alicja Jereczek-Fossa, Andrea Lancia, Gianluca Ingrosso, Filippo Alongi, Shafak Aluwini, Stefano Arcangeli, Pierre Blanchard, Antonio Conde Moreno, Felipe Couñago, Gilles Créhange, Piet Dirix, Alfonso Gomez Iturriaga, Matthias Guckenberger, David Pasquier, Paul Sargos, Marta Scorsetti, Stéphane Supiot, Alison C. Tree, Almudena Zapatero, Jennifer Le Guevelou, Piet Ost, Claus Belka, Producción Científica UCH 2022, UCH. Departamento de Medicina y Cirugía, and Guided Treatment in Optimal Selected Cancer Patients (GUTS)
- Subjects
Male ,Consensus ,Prostate cancer ,SBRT ,Delphi Technique ,Radiotherapy ,Elective nodal radiotherapy ,Próstata - Cáncer - Tratamiento ,Prostatic Neoplasms ,Prostate - Cancer - Radiotherapy ,Hematology ,Prostate - Cancer - Treatment ,Oncology ,Próstata - Cáncer - Radioterapia ,ESTRO-ACROP ,Humans ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Oligometastases ,Retrospective Studies - Abstract
Este artículo se encuentra disponible en la siguiente URL: https://www.sciencedirect.com/science/article/pii/S0167814022044991?via%3Dihub En este artículo de investigación también participan:Gianluca Ingrosso, Filippo Alongi, Shafak Aluwini, Stefano Arcangeli, Pierre Blanchard, Felipe Couñago, Gilles Créhange, Piet Dirix, Alfonso Gomez Iturriaga, Matthias Guckenberger, David Pasquier, Paul Sargos, Marta Scorsetti, Stéphane Supiot, Alison C. Tree, Almudena Zapatero, Jennifer Le Guevelou, Piet Ost y Claus Belka. Background and purpose: Oligometastatic prostate cancer is a new and emerging treatment field with only few prospective randomized studies published so far. Despite the lack of strong level I evidence, metastasis-directed therapies (MDT) are widely used in clinical practice, mainly based on retrospective and small phase 2 studies and with a large difference across centers. Pending results of ongoing prospective randomized trials, there is a clear need for more consistent treatment indications and radiotherapy practices. Material and methods: A European Society for Radiotherapy and Oncology (ESTRO) Guidelines Committee consisting of radiation oncologists’ experts in prostate cancer was asked to answer a dedicated questionnaire, including 41 questions on the main controversial issues with regard to oligometastatic prostate cancer. Results: The panel achieved consensus on patient selection and routine use of prostate-specific membrane antigen positron emission tomography (PSMA PET) imaging as preferred staging and restaging imaging. MDT strategies are recommended in the de novo oligometastatic, oligorecurrent and oligoprogressive disease setting for nodal, bone and visceral metastases. Radiation therapy doses, volumes and techniques were discussed and commented. Conclusion: These recommendations have the purpose of providing standardization and consensus to optimize the radiotherapy treatment of oligometastatic prostate cancer until mature results of randomized trials are available.
- Published
- 2022