1. Central Lymphatic Irradiation to Low Dose for Advanced Nodular Lymphoreticular Tumors (Non-Hodgkin's Lymphoma)
- Author
-
James D. Cox
- Subjects
Adult ,Male ,medicine.medical_specialty ,Lymphoma ,Entire abdomen ,Wisconsin ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Cobalt Radioisotopes ,Stage (cooking) ,Generalized Disease ,Lymphatic Irradiation ,Aged ,business.industry ,Lymphoma, Non-Hodgkin ,Low dose ,Radiotherapy Dosage ,Middle Aged ,medicine.disease ,Non-Hodgkin's lymphoma ,Surgery ,Female ,Lymphoma, Large B-Cell, Diffuse ,Neoplasm Recurrence, Local ,Radioisotope Teletherapy ,business - Abstract
Total central lymphatic irradiation (2500-3000 rads in 3 to 6 weeks) including the entire abdomen, the supradiaphragmatic nodal areas, and Waldeyer's ring is being investigated as a potentially curative approach to patients with Stage III disease. Twenty-two patients have been treated (24-month minimum observation). All evidence of disease has disappeared in every patient. Three patients have developed local recurrence; 2 of them received 2000 rads or less. Three patients had marginal recurrences, and 5 developed generalized disease involving viscera. Fourteen patients (64%) are alive and free of any evidence of disease from 24-90 months (median, 54 months). Absolute survival is 82% (18/22).
- Published
- 1978
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