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Your search keyword '"Whitmore, G"' showing total 16 results
Start Over Author "Whitmore, G" Journal radiation research
16 results on '"Whitmore, G"'

12. Cell-cycle-stage specificity of 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and interaction with ionizing radiation in mammalian cell cultures.

Author

Wilson WR and Whitmore GF

Subjects
Amsacrine, Animals, Antineoplastic Agents pharmacology, Cells, Cultured, Cricetinae, Cricetulus, Cytological Techniques, Dose-Response Relationship, Drug, Dose-Response Relationship, Radiation, Female, Ovary, Radiation, Ionizing, Aminoacridines pharmacology, Cell Cycle drug effects, Cell Survival
Published
1981

13. The radiation reduction in misonidazole.

Author

Whillans DW and Whitmore GF

Subjects
Chromatography, High Pressure Liquid, Free Radicals, Misonidazole analogs & derivatives, Misonidazole metabolism, Oxidation-Reduction, Spectrum Analysis, Misonidazole radiation effects, Nitroimidazoles radiation effects
Published
1981

14. A comparison of radiation-sensitizing ability and cell uptake for NDPP and Ro-07-0582.

Author

Wong TW and Whitmore GF

Subjects
Animals, Cells, Cultured, Chromatography, Cricetinae, Indicators and Reagents, Nitro Compounds, Nitrobenzenes metabolism, Propiophenones metabolism, Radiation-Sensitizing Agents metabolism, Sulfhydryl Compounds analysis, Nitroimidazoles pharmacology, Propiophenones pharmacology, Radiation-Sensitizing Agents pharmacology, Sulfhydryl Compounds metabolism
Published
1977

15. DNA repair-deficient Chinese hamster ovary cells exhibiting differential sensitivity to gamma rays under aerobic and hypoxic conditions.

Author

Rubin JS and Whitmore GF

Subjects
Aerobiosis, Anaerobiosis, Animals, Cell Line, Cobalt Radioisotopes, Cricetinae, Cricetulus, Dose-Response Relationship, Radiation, Female, Gamma Rays, In Vitro Techniques, Mutation, Radiation Tolerance, Cell Survival radiation effects, DNA Repair, Oxygen physiology
Abstract

The survival of the wild-type parent and two mutant lines of Chinese hamster cells, known to be defective in DNA repair, has been determined as a function of exposure to gamma rays under aerobic and hypoxic conditions. When compared to the wild-type line, one of the mutants selected for sensitivity to ethyl methyl sulfonate (EMS), and known to be defective in the repair of DNA strand breaks, exhibits a markedly enhanced sensitivity to aerobic irradiation but a reduced enhancement to hypoxic irradiation and thus an enhanced oxygen enhancement ratio (OER). In contrast, the other line, known to be defective in the incision step of excision repair, exhibits the reverse pattern of sensitivity and hence a reduced OER. The results are compared to findings in bacterial mutants and cells obtained from ataxia telangiectasia (AT) patients and heterozygotes.

Published
1985

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