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Your search keyword '"Barberet, P."' showing total 3 results
Start Over Author "Barberet, P." Journal radiation protection dosimetry
3 results on '"Barberet, P."'

3. Monte Carlo dosimetry for targeted irradiation of individual cells using a microbeam facility.

Author

Incerti S, Seznec H, Simon M, Barberet P, Habchi C, and Moretto P

Subjects
Computer Simulation, Humans, Models, Statistical, Monte Carlo Method, Radiotherapy Dosage, Algorithms, Cell Physiological Phenomena radiation effects, Models, Biological, Radiometry methods, Radiotherapy Planning, Computer-Assisted methods, Radiotherapy, Conformal methods
Abstract

Microbeam facilities provide a unique opportunity to investigate the effects of ionising radiation on living biological cells with a precise control of the delivered dose. This paper describes dosimetry calculations performed at the single-cell level in the microbeam irradiation facility available at the Centre d'Etudes Nucléaires de Bordeaux-Gradignan in France, using the object-oriented Geant4 Monte Carlo simulation toolkit. The cell geometry model is based on high-resolution three-dimensional voxelised phantoms of a human keratinocyte (HaCaT) cell line. Such phantoms are built from confocal microscopy imaging and from ion beam chemical elemental analysis. Results are presented for single-cell irradiation with 3 MeV incident alpha particles.

Published
2009
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