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Paleoparasitology is the study of parasite remains from archaeological and paleontological sites. Raptor pellets can be used as source for paleoparasitological information in archaeological sites. However, this zooarchaeological material has been scarcely studied. Epullán Chica (ECh) is an archaeological site in northwestern Patagonia. This cave yielded remains from more than 2000 years before present. The aim of this paper was to study the parasite remains found in owl pellets from the archaeological site ECh, and to discuss the paleoparasitological findings in an archaeological context. Twenty two raptor pellets were examined for parasites. The pellets were whole processed by rehydration in a 0.5% water solution of trisodium phosphate, followed by homogenization, filtered and processed by spontaneous sedimentation. Eight out of 22 bird pellets examined were positive for parasites from reptiles and rodents. Representatives of 12 parasite taxa were recorded; nine of this parasitic species were reported for the first time from ancient samples from Patagonia. This is the first time that pellets give evidences of ancient reptile parasites from archaeological contexts. It is noteworthy that Late Holocene hunter-gatherers of the upper Limay River basin, could have been exposed to some of these zoonotic parasites. Future paleoparasitological studies on owl pellets may reflect even more the parasitological diversity of all micromammal and reptile species presents in ancient times. [ABSTRACT FROM AUTHOR]