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Aim Although socioeconomic background is known to impact on the incidence and progression of chronic kidney disease, its influence of on the presentation and outcome for acute kidney injury is not known and is the subject of this study. Design The Welsh National electronic AKI reporting system was used to identify all cases of AKI in patients >18 years of age between March 2015 and November 2017. Methods Socioeconomic classification of patients was derived from the Welsh Index Multiple Deprivation score (WIMD). Patients were grouped according to the WIMD score by their postcode, and the ranked data were categorized into percentiles and correlated with incidence and measures of AKI severity and outcome. Results Date was collected on a total of 57 654 patients. Increased deprivation was associated with higher AKI incidence rates, more episodes of AKI per patient and more severe AKI at presentation. In contrast 90-day mortality was highest in the most affluent areas. Mortality in affluent areas was driven by increased patient age. Corrected for age 90-day mortality was higher in areas of increased deprivation. Conclusion This study highlights that AKI incidence presentation and outcomes are adversely affected by social deprivation. Further studies are required to understand the extent to which these differences reflect patient related factors or regional differences in provision and access to care. [ABSTRACT FROM AUTHOR]

The second review by Dr Gupta and colleagues of the Institute of Post Graduate Medical Education and Research, West Bengal, India relates to the rarer occurrence of herpes simplex encephalitis in the post-acute COVID-19 infection period. Does anti-viral treatment in acute COVID infection decrease the risk of developing the Long-COVID Syndrome? It was W.B. Yeats, Nobel Laureate and renowned poet who once wrote: Education is not the filling of a pail but the lighting of a fire As the academic home for Translational Medicine, the Association seeks to promote and sustain this lighting of that fire of scientific curiosity. [Extracted from the article]