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Background: Influenza vaccination has been associated with decreased risk of influenza‐related infections. However, associations between influenza vaccination and the severity of influenza cases have not been systematically summarized. We conducted a meta‐analysis to evaluate whether influenza vaccination could attenuate symptom severity in vaccinated influenza patients. Methods: A systematic literature search was performed using the PubMed, Web of Science, EMBASE, and Scopus databases. A quantitative synthesis of the data was conducted using a fixed/random effects model in the meta‐analysis. Results: A total of seven studies, involving 6342 vaccinated and 7036 non‐vaccinated patients were included. Compared with non‐vaccinated, vaccinated patients were significantly less likely to develop a fever (OR = 0.66, 95% CI: 0.43–0.89), be admitted to the ICU (OR = 0.79, 95% CI: 0.64–0.97), suffer mortality (OR = 0.55, 95% CI: 0.34–0.89), stay in the ICU (WMD = ‐1.37, 95% CI: ‐2.15 to ‐0.60) or stay in the hospital (WMD = ‐0.32, 95% CI: ‐0.61 to ‐0.04). Conclusion: Those benefits that could be highlighted in the communication material to enhance the uptake of influenza vaccination among both the public health nurses and the community as a whole. [ABSTRACT FROM AUTHOR]