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Your search keyword '"Mahmoud Reza Azarpajouh"' showing total 2 results
Start Over Author "Mahmoud Reza Azarpajouh" Journal psychoneuroendocrinology
2 results on '"Mahmoud Reza Azarpajouh"'

1. Depression and anxiety symptoms are associated with white blood cell count and red cell distribution width: A sex-stratified analysis in a population-based study

Author

Majid Ghayour-Mobarhan, Zahra Ghaneifar, Seyed Mahdi Hassanian, Mohsen Moohebati, Mohsen Nematy, Mojtaba Shafiee, Gordon A. Ferns, Zahra Khorasanchi, Maryam Tayefi, Naghmeh Mokhber, Habibolah Esmaeili, Hamideh Safarian, Mohammad Safarian, Mahmoud Reza Azarpajouh, Amir Avan, Mohammad Reza Parizadeh, Farzad Rahmani, Mahmoud Ebrahimi, and Alireza Heidari-Bakavoli

Subjects
Adult, Erythrocyte Indices, Male, medicine.medical_specialty, Erythrocytes, Endocrinology, Diabetes and Metabolism, Population, Anxiety, Iran, 03 medical and health sciences, Hemoglobins, Leukocyte Count, 0302 clinical medicine, Endocrinology, Sex Factors, White blood cell, Internal medicine, medicine, Humans, 030212 general & internal medicine, education, Biological Psychiatry, Depression (differential diagnoses), Inflammation, education.field_of_study, Depressive Disorder, Major, medicine.diagnostic_test, Endocrine and Autonomic Systems, business.industry, Depression, Complete blood count, Red blood cell distribution width, Middle Aged, medicine.disease, Psychiatry and Mental health, medicine.anatomical_structure, Mood disorders, Cohort, Immunology, Female, medicine.symptom, business, 030217 neurology & neurosurgery, Biomarkers
Abstract

Background: Depression and anxiety are two important mood disorders that are frequently associated with chronic diseases such as cardiovascular diseases (CVDs). Hyper-inflammation is related to both CVDs and psychiatric conditions such as depression and anxiety. Therefore, inflammation may partially explain the relationship between depression and cardiovascular disease.\ud \ud Objective: The objective of this study was to investigate the association between symptoms of depression/anxiety disorders and serum hs-CRP and inflammation linked conditions in a large Iranian population. \ud Methods: Symptoms of depression and anxiety disorders and serum hs-CRP levels were measured in 9,759 participants (40% males and 60% females) enrolled in MASHAD study. Symptoms of depression and anxiety were evaluated with Beck Depression and Anxiety Inventories. According to the scores of depression and anxiety, individuals were categorized into four groups of no or minimal, low, moderate and severe categories.\ud \ud Results: The median serum hs-CRP concentration increased with increasing severity of depression and anxiety disorders. Male participants with severe depression had significantly higher levels of hs-CRP (p

Published
2017

2. Depression and anxiety both associate with serum level of hs-CRP: A gender-stratified analysis in a population-based study

Author

Mohsen Moohebati, Mojtaba Shafiee, Naghmeh Mokhber, Mohammad Safarian, Habibolah Esmaeili, Gordon A. Ferns, Mahmoud Reza Azarpajouh, Majid Ghayour-Mobarhan, Zahra Ghaneifar, Susan Darroudi, Mahmoud Ebrahimi, Alireza Heidari-Bakavoli, Maryam Tayefi, Samaneh Khakpouri, Mohsen Nematy, Seyyed Mohammad Reza Kazemi-Bajestani, Mohammad Reza Parizadeh, and Maryam Mohammadi

Subjects
Adult, Male, Endocrinology, Diabetes and Metabolism, Population, Disease, Anxiety, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Sex Factors, Risk Factors, medicine, Humans, education, Biological Psychiatry, Depression (differential diagnoses), Aged, education.field_of_study, Endocrine and Autonomic Systems, Depression, Middle Aged, medicine.disease, Obesity, 030227 psychiatry, Population based study, Psychiatry and Mental health, C-Reactive Protein, Mood disorders, Case-Control Studies, Cohort, Female, medicine.symptom, Psychology, 030217 neurology & neurosurgery, Clinical psychology
Abstract

Depression and anxiety are two important mood disorders that are frequently associated with chronic diseases such as cardiovascular diseases (CVDs). Hyper-inflammation is related to both CVDs and psychological conditions such as depression and anxiety. Therefore, inflammation may partially explain the relationship between depression and cardiovascular disease.The objective of this study was to perform a gender-stratified examination of the association between symptoms of depression/anxiety disorders and serum hs-CRP and inflammation linked conditions in a large Iranian population.Symptoms of depression and anxiety disorders and serum hs-CRP levels were measured in 9759 participants (40% males and 60% females) aged 35-65 years, enrolled in a population-based cohort (MASHAD) study in north-eastern Iran. Symptoms of depression and anxiety were evaluated with Beck Depression and Anxiety Inventories. According to the scores of depression and anxiety, individuals were categorized into four groups of no or minimal, low, moderate and severe categories.The median serum hs-CRP concentration increased with increasing severity of depression and anxiety disorders. Male participants with severe depression had significantly higher levels of hs-CRP (p0.001); however, this relationship was less marked among women (p=0.04). Subjects with severe anxiety also had significantly higher levels of hs-CRP (p0.001). Moreover, women with severe depression and anxiety had higher BMI. There was also a positive association between current smoking habit and depression/anxiety disorders.Depression and anxiety disorders are associated with elevated levels of hs-CRP, particularly among men. Also, there is a significant positive association between depression/anxiety disorders and inflammation linked conditions such as smoking and obesity; however, in the case of obesity this association is only present in women.

Published
2016

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