1. Slower processing speed after treatment for pediatric brain tumor and acute lymphoblastic leukemia
- Author
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Xiaoping Xiong, Heather M. Conklin, Lisa S. Kahalley, Melissa M. Hudson, Vida L. Tyc, Stephanie J. Wilson, Pamela S. Hinds, and Shengjie Wu
- Subjects
Pediatrics ,medicine.medical_specialty ,Lymphoblastic Leukemia ,Wechsler Adult Intelligence Scale ,Experimental and Cognitive Psychology ,Cognition ,Grade retention ,Pediatric cancer ,Cognitive test ,Psychiatry and Mental health ,Oncology ,medicine ,Cognitive decline ,Psychology ,After treatment - Abstract
Background Acute lymphoblastic leukemia (ALL) and brain tumor (BT) survivors are at risk for post-treatment IQ declines. The extent to which lower scores represent global cognitive decline versus domain-specific impairment remains unclear. This study examined discrepancies between processing speed and estimated IQ (EIQ) scores and identified clinical characteristics associated with score discrepancies in a sample of pediatric cancer survivors. Procedure Survivors (50 ALL, 50 BT) ages 12–17 years completed cognitive testing. The Wechsler Abbreviated Scale of Intelligence provided an untimed measure of general reasoning ability (EIQ). The age-appropriate Wechsler Intelligence Scale provided a Processing Speed Index (PSI) score. Scores were examined and compared. Results Survivors' PSI scores were lower than their EIQ scores (BT t(45) = 6.3, p
- Published
- 2013
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