1. Health‐related quality of life, psychosocial functioning, and unmet health needs in patients with sarcoma: A systematic review
- Author
-
Jessica Reid, Jaklin Eliott, Phyllis Butow, Susan J. Neuhaus, Joshua McDonough, McDonough, Joshua, Eliott, Jaklin, Neuhaus, Susan, Reid, Jessica, and Butow, Phyllis
- Subjects
Male ,medicine.medical_specialty ,psychosocial issues ,sarcoma ,Health Status ,Population ,neoplasms ,Experimental and Cognitive Psychology ,Anxiety ,03 medical and health sciences ,0302 clinical medicine ,Cancer Survivors ,Quality of life ,cancer ,Humans ,Medicine ,Patient Reported Outcome Measures ,030212 general & internal medicine ,education ,Depression (differential diagnoses) ,Randomized Controlled Trials as Topic ,education.field_of_study ,Depression ,business.industry ,unmet service needs ,Sarcoma ,medicine.disease ,humanities ,Psychiatry and Mental health ,Distress ,Mental Health ,quality of life ,Oncology ,psycho‐oncology ,030220 oncology & carcinogenesis ,Family medicine ,oncology ,Quality of Life ,Female ,medicine.symptom ,business ,Psychosocial ,Qualitative research - Abstract
Objective: Health-related quality of life (HRQoL), psychosocial distress, and unmet health needs are important patient-reported outcomes (PROs) for patients with sarcoma treated with curative intent. Syntheses of data on these PROs in patients with sarcoma are limited. Methods: A systematic review of peer-reviewed literature published between 2007 and 2017 was conducted using five databases, guided by the PRISMA and Cochrane reporting guidelines. Results: Of 7240 articles identified, 31 were included in this review. Compared with healthy individuals, patients with sarcoma frequently scored lower in physical and psychological HRQoL domains and experienced higher rates of self-image issues, depression, and suicide. However, outcomes for patients with sarcoma were relatively comparable to those with other malignancies. Anxiety symptoms were more common in the diagnosis phase, while depressive symptoms were more common in the treatment phase. Patients who are older, female, and socially isolated often reported lower HRQoL. As a sarcoma-specific HRQoL instrument is not available, and all studies have used generic instruments, key issues may have been omitted. Conclusion: There are few studies reporting data for HRQoL, psychosocial issues, or unmet health needs in this population. A sarcoma-specific HRQoL instrument is needed to accurately describe outcomes in this population. There is a need for further qualitative research to conceptualise the HRQoL issues relevant to this population, against which to map existing HRQoL instruments and guide adaptation or creation of a new instrument. Refereed/Peer-reviewed
- Published
- 2019