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Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the clinical effect of four oral vitamins [vitamin E (Vit E) + folic acid (FA)+ vitamin B2 (Vit B2) + vitamin B12 (Vit B12)] combined with FE complex enzyme rash on the recurrent oral ulcer (ROU) and on the serum inflammatory factors levels. Methods: 126 cases with ROU in our hospital from January 2014 to February 2016 were selected as research objectives and randomly divided into two groups. FE complex enzyme was provided to the control group, while FE complex enzyme and four Vietnam (Vit E+FA+Vit B2+Vit B12) were given to the observation group. The local efficacy, long-term efficacy, serum inflammatory factor levels before and after treatment as well as the incidence of adverse drug reactions were recorded and compared between two groups. Results: Compared with the control group, the pain index was significantly decreased on 30th treating day in the observation group(P<0.01), and the average ulcer period was shorten (P<0.01). After being treated for 6 months, the overall effective rate was 95.2% in the observation group, which was significantly higher than that of the control group (81.0%, P<0.05). The serum TNF-α and IL-17 levels on the 30th treating day was significantly lower in both groups after treatment than those before treatment (P<0.01), but the serum IL-2 level was significantly increased (P<0.01), and the improvement of each above inflammatory factors in the observation group were more significant than those of the control group (P<0.01). No significant difference was found in the incidence of adverse reactions between two groups (P>0.05). Conclusions: Four oral Vietnam combined with FE complex enzyme could promote the ulcer wound healing, reduce the pain, regulate the body to promote/anti-inflammatory factor balance and improve the long-term efficacy in the treatment of patients with ROU with high safety. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the relationship between serum parathyroid hormone (PTH) level and nutritional status in patients with chronic renal failure (CRF) who had taken the maintenance hemodialysis therapy. Methods: 98 cases with chronic renal failure who were treated with maintenance hemodialysis in our hospital from August 2013 to October 2015 were selected as the study group, and another 69 healthy volunteers were chosen to be the control group. Then the levels of PTH. HDL-C. LDL-C. CRP. BUN. SCr. TP. ALB. TC, TG and Hb in the serum of patients were detected by radioimmunoassay. The nutritional status of the two groups was evaluated by mini nutritional assessment (MNA). and the correlation between serum PTH and serum biochemical parameters was evaluated by Spearman correlation analysis. Results: The incidence of malnutrition in the study group was 31.63%, which was higher than 13.04% in the control group (P<0.05): The levels of PTH. HDL-C. LDL-C. CRP. BUN and SCr in the serum of CRF patients with malnutrition were higher than those of the patients with latent malnutrition and balanced nutrition, and the levels of TP. ALB. TC, TG and Hb were lower (P<0.05): The levels of PTH. HDL-C. LDL-C. CRP. BUN and SCr in the serum of CRF patients with latent malnutrition were higher than those of the patients with balanced nutrition, and the levels of TP. ALB. TC, TG and Hb were lower (P<0.05); There was positive relationship between PTH and BUN and SCr (P<0.05): There was negative relationship between PTH and MNA. TP. TC. TG. CRP and Hb (P<0.05): There was no correlation between PTH and ALB. HDL-C and LDL-C (P>0.05). Conclusion: High levels of PTH in the serum CRF patients was the risk factor of malnutrition, which should pay more attention in the clinical field. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Biofilms dramatically increase the bacterial antibiotic resistance(1000-fold increased compared with the planktonic cells) and environmental stress resistance(temperature, stress, oxidant, and p H). On the other hand, the medical implant intrusion caused the immunity decreasing. Hence, the biofilms bring a higher infection risk for biomaterial implantation. The bacterial composition and mechanism for biofilm development are critical for future biomaterial development. The modification of medical implants is accomplished by changing the material type or covering a surface coating, which both change the physicochemical properties of the material surface. In this review we listed the mechanism and examples for biofilm inhibition via antibiotics, metal ions, oxides,QS-related molecules, and enzymes. In the end, we also talked about the future trends for biofilm control methods. [ABSTRACT FROM AUTHOR]