Author: "Wolfer, David P." / Journal: proceedings of the national academy of sciences of the united states of america - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Wolfer, David P." Journal proceedings of the national academy of sciences of the united states of america

Author: Luo, Wenshu, Egger, Matteo, Domonkos, Andor, Que, Lin, Lukacsovich, David, Cruz-Ochoa, Natalia Andrea, Szőcs, Szilárd, Seng, Charlotte, Arszovszki, Antónia, Sipos, Eszter, Amrein, Irmgard, Winterer, Jochen, Lukacsovich, Tamás, Szabadics, János, Wolfer, David P., Varga, Csaba, and Földy, Csaba
Published: 2021

Author: Magara, Fulvio, Müller, Ulrike, Li, Zhi-Wei, Lipp, Hans-Peter, Weissmann, Charles, Stagljar, Marijana, and Wolfer, David P.
Published: 1999

Author: Huang, Yan-You, Bach, Mary Elizabeth, Lipp, Hans-Peter, Zhuo, Min, Wolfer, David P., Hawkins, Robert D., Schoonjans, Luc, Kandel, Eric R., Godfraind, Jean-Marie, Mulligan, Richard, Collen, D., and Carmeliet, Peter
Published: 1996

Author: Coomaraswamy, Janaky, Kilger, Ellen, Wölfing, Heidrun, Schäfer, Claudia, Kaeser, Stephan A., Wegenast-Braun, Bettina M., Hefendehl, Jasmin K., Wolburg, Hartwig, Mazzella, Matthew, Ghiso, Jorge, Goedert, Michel, Akiyama, Haruhiko, Garcia-Sierra, Francisco, Wolfer, David P., Mathews, Paul M., Jucker, Mathias, and Südhof, Thomas C.
Published: 2010

Author: Berger, Stefan, Wolfer, David P., Selbach, Oliver, Alter, Heike, Erdmann, Gitta, Reichardt, Holger M., Chepkova, Aisa N., Welzl, Hans, Haas, Helmut L., Lipp, Hans-Peter, and Schütz, Günther
Published: 2006
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Author: WenshuLuo, Egger, Matteo, Domonkos, Andor, Lin Que, Lukacsovich, David, Cruz-Ochoa, Natalia Andrea, Szocs, Szilárd, Seng, Charlotte, Arszovszki, Antónia, Sipos, Eszter, Amrein, Irmgard, Winterer, Jochen, Lukacsovich, Tamás, Szabadics, János, Wolfer, David P., Varga, Csaba, and Földy, Csaba
Subjects: PLANT fibers, ADULTS, GRANULE cells, CENTRAL nervous system, HIPPOCAMPUS (Brain), PROBLEM solving
Abstract: Circuit formation in the central nervous system has been historically studied during development, after which cell-autonomous and nonautonomous wiring factors inactivate. In principle, balanced reactivation of such factors could enable further wiring in adults, but their relative contributions may be circuit dependent and are largely unknown. Here, we investigated hippocampal mossy fiber sprouting to gain insight into wiring mechanisms in mature circuits. We found that sole ectopic expression of Id2 in granule cells is capable of driving mossy fiber sprouting in healthy adult mouse and rat. Mice with the new mossy fiber circuit solved spatial problems equally well as controls but appeared to rely on local rather than global spatial cues. Our results demonstrate reprogrammed connectivity in mature neurons by one defined factor and an assembly of a new synaptic circuit in adult brain. [ABSTRACT FROM AUTHOR]
Published: 2021
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