1. [Andrological characteristics in males with X-chromosomal pathology]
- Author
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I F, Iunda, V D, Dyshlovoĭ, L P, Imshinetskaia, G N, Koblianskaia, and L N, Ryzhkova
- Subjects
Adult ,Male ,Sex Characteristics ,X Chromosome ,Adolescent ,Anthropometry ,Estrogens ,17-Ketosteroids ,Klinefelter Syndrome ,Sex Chromatin ,Humans ,Female ,Testosterone ,Physical Examination - Abstract
The authors examined 32 patients with Klinefelter's syndrome: 21 with chromatine-positive (the 1st group), 11 with chromatine-negative (the 2nd group). In contrast to the patients of the 2nd group an altered karyotype was revealed in patients of the 1st group (47/XXY, 46XY/47XXY, 48XXXY/49XXXXY). Hormonal examination revelaed hypoandrogenia with a relative hyperestrogenuria in the majority of the patients of the 1st and 2nd groups. However, patients of the 2nd group displayed a greater preservation of the reserve testicular function. Further clinical, endocrinological and cytogenetic studies of the Klinefelter's syndrome is necessary for its differential diagnosis and correction.
- Published
- 1979