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Start Over Author "Schrub JC" Journal presse medicale paris france 1983
7 results on '"Schrub JC"'

4. [Medical treatment of prolactin-secreting pituitary adenomas. Influence of the size of the adenoma].

Author

Kuhn JM, Gancel A, Weinstein A, Courtois H, Schrub JC, Tadie M, and Wolf LM

Subjects
Adenoma metabolism, Adenoma pathology, Adult, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neoplasm Staging, Pituitary Neoplasms metabolism, Pituitary Neoplasms pathology, Prolactin blood, Radiography, Sella Turcica diagnostic imaging, Adenoma drug therapy, Bromocriptine therapeutic use, Pituitary Neoplasms drug therapy, Prolactin metabolism
Abstract

Forty-two patients with prolactin-secreting pituitary adenoma (prolactinoma) demonstrated by a radiologically abnormal sella turcica and hyperprolactinaemia were treated with bromocriptine. Baseline serum prolactin levels, which before treatment correlated with the size of the adenoma, returned to normal under bromocriptine in 30 out of 36 cases; in 6 female patients, however, they were lowered but remained moderately high. The dose of bromocriptine and the time required for normalization of prolactinaemia correlated with the size of the tumour. In 11 patients with macroadenoma bromocriptine dosage and prolactinaemia were inversely correlated; in 8 of these the adenoma was reduced in size. In 12 cases where the long-term treatment was interrupted, prolactinaemia rose again, suggesting that the medical treatment alone has no lasting curative effect.

Published
1985

7. [Testicular Leydig cell tumor. A case].

Author

Gancel A, Vuillermet P, Ozenne G, Courtois H, and Schrub JC

Subjects
Adult, Humans, Male, Hormones metabolism, Leydig Cell Tumor metabolism, Testicular Neoplasms metabolism
Published
1984

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